This paper reports on new research into the timing and nature of post-glacial environmental change at Lake Flixton (North Yorkshire, UK). Previous investigations indicate a succession of wetland environments during the early Holocene, ultimately infilling the basin by ca 7,000 cal bp. The expansion of wetland environments, along with early Holocene woodland development, has been linked to changes in the human occupation of this landscape during the Mesolithic (ca 11,300-6,000 cal bp). However, our understanding of the timing and nature of environmental change within the palaeolake is poor, making it difficult to correlate to known patterns of Mesolithic activity. This paper provides a new record for both the chronology and character of environmental change within Lake Flixton, and discusses the implications for the Mesolithic occupation of the surrounding landscape.