Abstract:INTRODUCTIONPerimenopause, that so-called menopausal transition, is defined as the period (2-8 years) preceding menopause and the one-year period after final menses, resulting from the loss of ovarian follicular activity.1 [The loss of ovarian follicular activity causing some biological changes including the decrease in circulating estrogen levels. Estrogen deficiency accounts for irregular menstruation, diminished vaginal lubrication, changes in the vascular, muscular, and urogenital systems, and also alterat… Show more
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