Early gas chromatography/mass spectrometry

Gohlke, R. S.; McLafferty, Fred W.

doi:10.1016/1044-0305(93)85001-e

Cited by 147 publications

(65 citation statements)

References 29 publications

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“…See also liquid chromatography-mass spectrometry (LC-MS), supercritical fluid chromatography-mass spectrometry (SFC-MS), thin layer chromatography-mass spectrometry (TLC-MS). From [18,155].…”

Section: Notementioning

confidence: 99%

Definitions of terms relating to mass spectrometry (IUPAC Recommendations 2013)

Murray

Boyd

Eberlin

et al. 2013

Pure and Applied Chemistry

342

224

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This document contains recommendations for terminology in mass spectrometry. Development of standard terms dates back to 1974 when the IUPAC Commission on Analytical Nomenclature issued recommendations on mass spectrometry terms and definitions. In 1978, the IUPAC Commission on Molecular Structure and Spectroscopy updated and extended the recommendations and made further recommendations regarding symbols, acronyms, and abbreviations. The IUPAC Physical Chemistry Division Commission on Molecular Structure and Spectroscopy's Subcommittee on Mass Spectroscopy revised the recommended terms in 1991 and appended terms relating to vacuum technology. Some additional terms related to tandem mass spectrometry were added in 1993 and accelerator mass spectrometry in 1994. Owing to the rapid expansion of the field in the intervening years, particularly in mass spectrometry of biomolecules, a further revision of the recommendations has become necessary. This document contains a comprehensive revision of mass spectrometry terminology that represents the current consensus of the mass spectrometry community.

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Section: Notementioning

confidence: 99%

Definitions of terms relating to mass spectrometry (IUPAC Recommendations 2013)

Murray

Boyd

Eberlin

et al. 2013

Pure and Applied Chemistry

342

224

View full text Add to dashboard Cite

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“…Each extract components were eluted at different retention time from the gas chromatograph and the mass spectrometer captured, ionized, accelerated, deflected and detected each constituent separately (Gohlke and McLafferty, 1993).…”

Section: Gc-ms Characterizationmentioning

confidence: 99%

<i>Thaumatococcus daniellii</i> leaves: its chemical compositions, antioxidant and antimicrobial activities.

Hamid¹,

Aliyu²,

Abubakar³

et al. 2017

Ife Journal of Science

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The preliminary phytochemical investigation of n-hexane, ethyl acetate and methanol extracts of Thaumatococcus daniellii leaves revealed the presence of fats and oils, terpenoids, flavonoids, steroids and glycosides. The antimicrobial tests against some strains of bacteria and fungi showed inhibitions at moderate to high concentrations. Methanol extract of the plant exhibited low 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity with IC of 615.14 µg/ml. Gas chromatography-mass spectrometry (GC-MS) 50 characterization of n-hexane, ethylacetate and methanol extracts of T. daniellii leaves identified , thirteen and fifteen compounds, with tetracontane (28.76%) and L-ascorbic acid (15.07%); hexadecanoic acid (21.62%) and γ-sitosterol (11.06%); and naphthalene-1,2,3,5,6,7,8,8a-octahydro-1,8a-dimethyl-7-(1-methylethenyl)-,[1R(1.alpha.,7.beta.,8a.alpha.] (26.90%) and hexadecanoic acid (12.60%) being the major compounds respectively. The GC-MS analysis revealed various peaks of bioactive compounds of which the antioxidant and antimicrobial activities of the plant have been attributed to the prominent compounds in synergy with all the other compounds present in smaller quantities in the extracts.

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“…Polaroid photographs of the oscilloscope screen (Figure 3) ( Figure 2), and toluene. This first effort to interface GC with MS was only briefly or tardily described in the literature (36)(37)(38).…”

Section: Tandem Separation and Identification Methods 1955-1960mentioning

confidence: 99%

A Century of Progress in Molecular Mass Spectrometry

McLafferty

2011

Annual Rev. Anal. Chem.

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The first mass spectrum of a molecule was measured by J.J. Thomson in 1910. Mass spectrometry (MS) soon became crucial to the study of isotopes and atomic weights and to the development of atomic weapons for World War II. Its notable applications to molecules began with the quantitative analysis of light hydrocarbons during World War II. When I joined the Dow Chemical Company in 1950, MS was not favored by organic chemists. This situation improved only with an increased understanding of gaseous ion chemistry, which was obtained through the use of extensive reference data. Gas chromatography–MS was developed in 1956, and tandem MS was first used a decade later. In neutralization-reionization MS, an unusual, unstable species is prepared by ion-beam neutralization and characterized by reionization. Electrospray ionization of a protein mixture produces its corresponding ionized molecules. In top-down proteomics, ions from an individual component can be mass separated and subjected to collision-activated and electron-capture dissociation to provide extensive sequence information.

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Early gas chromatography/mass spectrometry

Cited by 147 publications

References 29 publications

Definitions of terms relating to mass spectrometry (IUPAC Recommendations 2013)

Definitions of terms relating to mass spectrometry (IUPAC Recommendations 2013)

<i>Thaumatococcus daniellii</i> leaves: its chemical compositions, antioxidant and antimicrobial activities.

A Century of Progress in Molecular Mass Spectrometry

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