<i>Thaumatococcus daniellii</i> leaves: its chemical compositions, antioxidant and antimicrobial activities.

Abstract

The preliminary phytochemical investigation of n-hexane, ethyl acetate and methanol extracts of Thaumatococcus daniellii leaves revealed the presence of fats and oils, terpenoids, flavonoids, steroids and glycosides. The antimicrobial tests against some strains of bacteria and fungi showed inhibitions at moderate to high concentrations. Methanol extract of the plant exhibited low 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity with IC of 615.14 µg/ml. Gas chromatography-mass spectrometry (GC-MS) 50 characterization of n-hexane, ethylacetate and methanol extracts of T. daniellii leaves identified , thirteen and fifteen compounds, with tetracontane (28.76%) and L-ascorbic acid (15.07%); hexadecanoic acid (21.62%) and γ-sitosterol (11.06%); and naphthalene-1,2,3,5,6,7,8,8a-octahydro-1,8a-dimethyl-7-(1-methylethenyl)-,[1R(1.alpha.,7.beta.,8a.alpha.] (26.90%) and hexadecanoic acid (12.60%) being the major compounds respectively. The GC-MS analysis revealed various peaks of bioactive compounds of which the antioxidant and antimicrobial activities of the plant have been attributed to the prominent compounds in synergy with all the other compounds present in smaller quantities in the extracts.

Synthesis and characterization of properties of aluminium coated Thaumatococcus daniellii extracts

“…1 shows that the inherent chemical components of Thaumatococcus daniellii (i.e. tetracontane (28.76%) and L-ascorbic acid (15.07%); hexadecanoic acid (21.62%) and c-sitosterol (11.06%) [19]) allows for the quick release of p-electrons to the aluminium atom.…”

Anti-inflammatory Activity of Ethanolic Leaf Extracts of Thaumatococus Danielli on Iodoacetamide Treated Rats

“…Thaumatococcus danielli is widely used to package food but have also been reported with various biological potentials such as antibacterial activity against some human pathogens (Segun et al, 2015), antihyperglycemic activity (Ajayi et al, 2019), and antioxidant activity (Ojekale et al, 2013, Adu et al, 2021. Several phytochemical components of the plant extracts such as, alkaloids, tannins, terpenoids, saponins, flavonoids, polyphenols, anthraquinones, cardiac glycosides, anthracene, glycosides (Ojekale et al, 2007, UKwubile et al, 2017, Hamid et al, 2017 have been suggested to be responsible for these biological activities, and there could also be a possible anti-inflammatory health benefit. Thus, in the present study, the anti-inflammatory activity of ethanolic leaf extract of T. danielli on iodoacetamide treated rats was investigated.…”

“…The leaves of this plant are commonly used to wrap food because they are believed to be safe, and also a source of herbal ingredients with potential health promoting properties (Dosumu and Akinnuoye, 2014). Secondary metabolites in T. danielli have been reported to include alkaloids, tannins, terpenoids, saponins, flavonoids, polyphenols, anthraquinones, cardiac glycosides, anthracene, glycosides (Ojekale et al, 2007, UKwubile et al, 2017, Hamid et al, 2017 with several biological activities such as antibacterial activity (Segun et al, 2015), antihyperglycemic activity (Ajayi et al, 2019), antioxidant activity (Ojekale et al, 2013, Adu et al, 2021 etc. Also, T. danielli have been traditionally claimed to possess anti-inflammatory activity, thus, the reason for this research to scientifically validate this claim on iodoacetamide treated rats.…”

Nutritional Composition and GC-MS Phytochemical Analysis of Thaumatococcus daniellii Leaves

“…These bioactive compounds found in Thaumatococcus daniellii leaf may not only play vital roles in the treatment of diseases but also act as organic food additives enhancing food values. The work of Hamid et al [13] also revealed the presence of fats and oils, terpenoids, flavonoids, steroids and glycosides in Thaumatococcus danielli leaf extracts while Oke et al [14] posited that T. daniellii containes flavonoids, polyphenols, alkaloids and saponins.…”

“…These bioactive compounds found in af may not only play vital roles in the treatment of diseases but also act as organic food additives enhancing food values. The work of Hamid et al [13] also revealed the presence of fats and oils, terpenoids, flavonoids, steroids and glycosides in leaf extracts while Oke T. daniellii leaves containes flavonoids, polyphenols, alkaloids and Vitamins are a group of organic compounds which are essential for normal physiological not synthesized ]. Our result shows leaf contained 3.1 g of Vitamin A.…”