Early farmers from across Europe directly descended from Neolithic Aegeans

Hofmanová, Zuzana; Kreutzer, Susanne; Hellenthal, Garrett; Sell, Christian; Diekmann, Yoan; Molino, David Díez del; Dorp, Lucy van; López, Saioa; Kousathanas, Athanasios; Link, Vivian; Kirsanow, Karola; Cassidy, Lara M.; Martiniano, Rui; Strobel, Melanie; Scheu, Amelie; Kotsakis, Kostas; Halstead, Paul; Triantaphyllou, Sevi; Kyparissi‐Apostolika, Nina; Urem-Kotsou, Dushanka-Christina; Ziota, Christina; Adaktylou, Fotini; Bobo, Dean; Winkelbach, Laura; Blöcher, Jens; Unterländer, Martina; Leuenberger, Christoph; Çilingiroğlu, Çiler; Horejs, Barbara; Gerritsen, Fokke; Shennan, Stephen; Bradley, Daniel G.; Currat, Mathias; Veeramah, Krishna R.; Wegmann, Daniel; Thomas, Mark G.; Papageorgopoulou, Christina; Bürger, Joachim

doi:10.1101/032763

Cited by 101 publications

(179 citation statements)

References 27 publications

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“…18) and no population structure in any of the four groups. 5 Moreover, the panmictic population model proposed would need to be compared against alternatives (eg, ref. 11).…”

Section: Resultsmentioning

confidence: 99%

Investigating mitochondrial DNA relationships in Neolithic Western Europe through serial coalescent simulations

et al. 2016

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Recent ancient DNA studies on European Neolithic human populations have provided persuasive evidence of a major migration of farmers originating from the Aegean, accompanied by sporadic hunter-gatherer admixture into early Neolithic populations, but increasing toward the Late Neolithic. In this context, ancient mitochondrial DNA data collected from the Neolithic necropolis of Gurgy (Paris Basin, France), the largest mitochondrial DNA sample obtained from a single archeological site for the Early/Middle Neolithic period, indicate little differentiation from farmers associated to both the Danubian and Mediterranean Neolithic migration routes, as well as from Western European hunter-gatherers. To test whether this pattern of differentiation could arise in a single unstructured population by genetic drift alone, we used serial coalescent simulations. We explore female effective population size parameter combinations at the time of the colonization of Europe 45000 years ago and the most recent of the Neolithic samples analyzed in this study 5900 years ago, and identify conditions under which population panmixia between hunter-gatherers/Early-Middle Neolithic farmers and Gurgy cannot be rejected. In relation to other studies on the current debate of the origins of Europeans, these results suggest increasing hunter-gatherer admixture into farmers' group migrating farther west in Europe.

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“…18) and no population structure in any of the four groups. 5 Moreover, the panmictic population model proposed would need to be compared against alternatives (eg, ref. 11).…”

Section: Resultsmentioning

confidence: 99%

Investigating mitochondrial DNA relationships in Neolithic Western Europe through serial coalescent simulations

et al. 2016

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“…145 We also generated 62 new direct radiocarbon dates (Extended Data Bronze Age Britain. We combined our data with previously published ancient DNA data [2][3][4][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37] 150 to form a genome-wide dataset of 476 ancient individuals (Supplementary Table 1). The 151 combined dataset included Beaker-associated individuals from Iberia (n=20), southern France 152 (n=4), northern Italy (n=1), central Europe (n=56), The Netherlands (n=9) and Britain (n=19).…”

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confidence: 99%

The Beaker Phenomenon and the Genomic Transformation of Northwest Europe

Olalde

Brace

Allentoft

et al. 2017

Preprint

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Bell Beaker pottery spread across western and central Europe beginning around 2750 BCE before disappearing between 2200–1800 BCE. The mechanism of its expansion is a topic of long-standing debate, with support for both cultural diffusion and human migration. We present new genome-wide ancient DNA data from 170 Neolithic, Copper Age and Bronze Age Europeans, including 100 Beaker-associated individuals. In contrast to the Corded Ware Complex, which has previously been identified as arriving in central Europe following migration from the east, we observe limited genetic affinity between Iberian and central European Beaker Complex-associated individuals, and thus exclude migration as a significant mechanism of spread between these two regions. However, human migration did have an important role in the further dissemination of the Beaker Complex, which we document most clearly in Britain using data from 80 newly reported individuals dating to 3900–1200 BCE. British Neolithic farmers were genetically similar to contemporary populations in continental Europe and in particular to Neolithic Iberians, suggesting that a portion of the farmer ancestry in Britain came from the Mediterranean rather than the Danubian route of farming expansion. Beginning with the Beaker period, and continuing through the Bronze Age, all British individuals harboured high proportions of Steppe ancestry and were genetically closely related to Beaker-associated individuals from the Lower Rhine area. We use these observations to show that the spread of the Beaker Complex to Britain was mediated by migration from the continent that replaced >90% of Britain’s Neolithic gene pool within a few hundred years, continuing the process that brought Steppe ancestry into central and northern Europe 400 years earlier.

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“…The analysis of north-western Anatolian Neolithic samples from the Marmara region in Turkey (Mathieson et al 2015), which also clearly cluster within the ancient Europeans' Neolithic pool, confirmed that the source of the agricultural incomers reached Europe through northern Anatolia, and probably followed a route across Greece to Europe (Hofmanová et al 2016).…”

Section: Further Readingmentioning

confidence: 66%

“…The admixture with local hunter-gatherers increased substantially at later stages (Haak et al 2015;Hofmanová et al 2016) at the transition to the Middle Neolithic across Europe, while Late Neolithic and Bronze Age periods were characterised by increasing input from steppe populations (Haak et al 2015).…”

Section: Further Readingmentioning

confidence: 99%

Genomic approaches and their contributions to understanding the European Neolithisation

Gamba

2016

Doc. praeh.

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The contribution of ancient DNA to the understanding of past events has been increasing exponentially in recent years. This is mainly due to the synergy of technical advances, such as the molecular technique of high-throughput DNA sequencing, which has allowed for the reconstruction of complete genomes as old as 750 000 years. Another step toward the cost-effective characterisation of ancient genomes is the sampling of petrous bone, which has allowed sequencing of the first ancient African genome. Here I review the significant contribution of ancient genomics to our understanding of the European Neolithisation process.

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Early farmers from across Europe directly descended from Neolithic Aegeans

Cited by 101 publications

References 27 publications

Investigating mitochondrial DNA relationships in Neolithic Western Europe through serial coalescent simulations

Investigating mitochondrial DNA relationships in Neolithic Western Europe through serial coalescent simulations

The Beaker Phenomenon and the Genomic Transformation of Northwest Europe

Genomic approaches and their contributions to understanding the European Neolithisation

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