Early Experience and Results of Bone Graft Enriched With Autologous Platelet Gel for Recalcitrant Nonunions of Lower Extremity

Chiang, Chao-Ching; Su, Chien-Ling; Huang, Chia-Sheng; Chen, Wei-Ming; Chen, Tain-Hsiung; Tzeng, Yun-Hsuan

doi:10.1097/01.ta.0000219937.51190.37

Cited by 22 publications

(19 citation statements)

References 23 publications

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“…Outcome following non-unions of the femoral shaft was one of the endpoints in the study of Chiang et al . After consolidation of the non-union, the investigators found significantly improved values concerning all sub-scores of the SF-36, including the intensity of pain [32]. Compared to our results, we suggest that healed non-unions do neither essentially lead to increased risk of pain nor seems the intensity to be different compared to patients with uneventful healing.…”

Section: Discussioncontrasting

confidence: 62%

The Aseptic Femoral and Tibial Shaft Non-Union in Healthy Patients – An Analysis of the Health-Related Quality of Life and the Socioeconomic Outcome

Zeckey

Mommsen²,

Andruszkow³

et al. 2011

TOORTHJ

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Long bone non-unions may lead to recurrent surgical procedures and in-hospital stays. Thus, restrictions of the health-related quality of life and of socioeconomic parameters might be expected. Knowledge of the impact on several parameters of professional life is sparse. Therefore, we analyzed the outcome in patients following non-unions of the tibial and femoral shaft after fracture compared to patients with uneventful healing.Material and Methodology:51 patients following non-unions of the the femoral (FNU) or tibial shaft (TNU) were compared to 51 patients (groups FH and TH) with uneventful fracture healing. Physical and mental health was assessed using the Short-Form Health Survey (SF-12), Hospital Anxiety and Depression Scale (HADS) and the Impact of Event Scale (IES). We also analyzed employment status and the usage of medical aids.Results:Scores of the SF-12 physical and psychological were lower in group TNU compared to group TH, the score of SF-12 physical but not psychological was significantly lower in group FNU compared to FH. Compared to uneventful healing, a significantly more frequent usage of medical aids was found in both non-union groups. A higher incidence of early retirement and unemployment was found in group FNU but not in group TNU.Conclusions:There is a profound influence on the quality of life following femoral or tibial non-unions after trauma. Compared to patients with uneventful fracture healing, patients with tibial and even more so femoral non-union show worse scores of the SF-12. Medical aids are frequently used following both, femoral and tibial non-unions. Not tibial, but femoral non-unions frequently lead to severe restrictions in professional life such as early retirement and unemployment.

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Section: Discussioncontrasting

confidence: 62%

The Aseptic Femoral and Tibial Shaft Non-Union in Healthy Patients – An Analysis of the Health-Related Quality of Life and the Socioeconomic Outcome

Zeckey

Mommsen²,

Andruszkow³

et al. 2011

TOORTHJ

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“…Existen tres estrategias biológicas básicas que prometen ser nuevas tecnologías en la reparación de fracturas: el uso de factores de crecimiento exó-geno, la terapia celular mesenquimal y la terapia génica [21][22][23][24] . Recientemente se han informado tratamientos con PRP utilizado inicialmente en cirugía oral para mejorar la osteointegración de implantes dentales [22][23][24][25] .…”

Section: Discussionunclassified

Plasma rico en plaquetas y su efecto en la regeneración ósea en fracturas mandibulares. Ensayo clínico controlado

Castillo-Cardiel

Medina-Quintana

Lomelí-Enríquez

et al. 2017

GMM

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“…Platelet gel has been studied in a variety of clinical settings including the treatment of burn injuries, spine surgery, lower extremity nonunions, sports medicine, and arthroplasty with varying results [1–3, 8–10]. Specifically, in total knee replacement patients, platelet gel has been reported to decrease blood loss, pain medication requirements, length of hospital stay, and rate of knee manipulation and improve postoperative knee range of motion [1–3].…”

Section: Discussionmentioning

confidence: 99%

Intraoperative Platelet Rich Plasma Usage in Total Knee Arthroplasty: Does It Help?

et al. 2013

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Autologous platelet rich plasma preparations, commonly referred to as platelet gel, have been reported to have benefits when used in total knee replacement of less blood loss and better motion, with few reported complications. This retrospective review of 268 consecutive primary total knee arthroplasty cases compares postsurgical range of motion at 2, 8, and 12 weeks, knee manipulation rates, change in hemoglobin, and complications between one group receiving a platelet gel preparation (135 cases), and an equivalent group receiving no platelet gel preparation (133 control cases). No difference was found between groups in manipulation rates, knee range of motion, or changes in hemoglobin (P > 0.05). The use of platelet gel in this study did not have a significant effect on hemoglobin at 72 hours postoperatively, knee range of motion, or manipulation rates up to 3 months post-op in this patient cohort.

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Early Experience and Results of Bone Graft Enriched With Autologous Platelet Gel for Recalcitrant Nonunions of Lower Extremity

Cited by 22 publications

References 23 publications

The Aseptic Femoral and Tibial Shaft Non-Union in Healthy Patients – An Analysis of the Health-Related Quality of Life and the Socioeconomic Outcome

The Aseptic Femoral and Tibial Shaft Non-Union in Healthy Patients – An Analysis of the Health-Related Quality of Life and the Socioeconomic Outcome

Plasma rico en plaquetas y su efecto en la regeneración ósea en fracturas mandibulares. Ensayo clínico controlado

Intraoperative Platelet Rich Plasma Usage in Total Knee Arthroplasty: Does It Help?

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