Early detection of congenital syphilis

Chowdhary, Nagalakshmi; Rani, Bs Kavya; Mukunda, K S; Kiran, N K

doi:10.4103/0970-4388.140969

Cited by 9 publications

(11 citation statements)

References 4 publications

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“…The lack of skeletal lesions on limb bones of B70 could be supported by clinical cases of late congenital syphilis, which found no periosteal lesions or perichondritis [69,70]. This may be related to the stage of infection in maternal syphilis and transmission [69].…”

Section: Differential Diagnosismentioning

confidence: 55%

Diagnosis of Mercurial Teeth in a Possible Case of Congenital Syphilis and Tuberculosis in a 19th Century Child Skeleton

Ioannou

Henneberg

et al. 2015

Journal of Anthropology

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Without the presence of “caries sicca,” “sabre shins,” and nodes/expansion of the long bones with superficial cavitation, differential diagnosis of venereal syphilis and tuberculosis (TB) may be difficult as various infections produce similar responses. However, congenital syphilis has distinctive features facilitating a diagnosis. A case study of remains of a juvenile European settler (probably male, 8–10 years old) (B70) buried in the 19th century and excavated in 2000 from the cemetery of the Anglican Church of St. Marys in South Australia is presented. B70 demonstrated that the two diseases might have been present in the same individual, congenital syphilis and TB. Widespread destruction of vertebral bodies and kyphosis-related rib deformations indicate advanced TB. Severe dental hypoplasia is limited to permanent incisors and first molars; there is pitting on the palate, periosteal reaction on the skull vault, and thinned clavicles. Dental signs are not limited to “screwdriver” central incisors and mulberry molars. Apical portions of the crowns of permanent upper, lower, central, and lateral incisors have multiple hypoplastic-disorganized defects; deciduous canines have severely hypoplastic crowns while possibly hypoplastic occlusal surfaces of lower deciduous second molars are largely destroyed by extensive caries. These dental abnormalities resemble teeth affected by mercurial treatment in congenital syphilitic patients as described by Hutchinson.

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Section: Differential Diagnosismentioning

confidence: 55%

Diagnosis of Mercurial Teeth in a Possible Case of Congenital Syphilis and Tuberculosis in a 19th Century Child Skeleton

Ioannou

Henneberg

et al. 2015

Journal of Anthropology

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“…These lesions called Hutchinson's teeth are the most common specific dental lesions (8). Because they are seen in the fixed teeth coming after the milk teeth, they are accepted as persistent symptoms (9). For this reason, regular teeth control is recommended for children after six years of age.…”

Section: Discussionmentioning

confidence: 99%

“…NTT examination and treatment according to the titre is recommended in the first control, at the third trimester and at birth. However, even in developed countries, only 68% of the pregnant women have regular follow-ups, and half of them have their first control at the end of the first trimester (9).…”

Section: Discussionmentioning

confidence: 99%

Management of Early Congenital Syphilis in a Newborn Case with Maculopapular Rash

Uygur¹,

Yaşar²,

Bal³

et al. 2017

jpr

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Öz ABS TRACTCongenital syphilis is preventable with proper antenatal follow-up and treatment of the pregnant woman infected with Treponema pallidum, and the rapid evaluation and early treatment of the newborns. Here we report a newborn with early congenital syphilis presenting with maculopapular rash and positive treponemal test born to an inadequately treated syphilitic mother. Keywords: Syphilis, congenital, maculopapular rash, newborn Konjenital sifiliz, Treponema pallidum ile enfekte olan annelerin prenatal dönemde düzenli izlem ve etkin tedavilerinin sağlanması, doğum sonrası bebeklerin hızla değerlendirilip erken tedavi edilmeleriyle önlenebilir. Burada annesi sifiliz tanısıyla yetersiz tedavi almış, makülopapüler döküntülerle başvuran maternal treponemal testi pozitif saptanarak erken konjenital sifiliz tanısıyla başarıyla tedavi edilen yenidoğan hasta sunulmaktadır. Anahtar Kelimeler: Sifiliz, konjenital, makülopapüler döküntü, yenidoğan Management of Early Congenital Syphilis in a Newborn Case with Maculopapular Rash

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“…It is one of the oldest identified infections, and still continues to prevail accounting for widespread global perinatal morbidity and mortality. 1 The main microorganism, i.e., T. pallidum, which is responsible for this infectious disease, after the 16th week of the intrauterine life, crosses through the placenta. Therefore, depending upon the time and extent of infection, it may patchily affect the facial structures.…”

Section: Introductionmentioning

confidence: 99%

“…It is also reported that 650,000 of these pregnancy difficulties result in perinatal death of the child. 1,[3][4][5][6][7][8] But, at times, due to a lack of acute symptoms or complications, manifestations of congenital syphilis may go unnoticed. This is a case report of a girl who presented to the outpatient department for dental problems and, on complete examination, was diagnosed with congenital syphilis.…”

mentioning

confidence: 99%