Early changes in kidney function following living donor nephrectomy

Samhan, M; Omar, Ahmed M.; Alsaeed, Talal; Al-Mousawi, M

doi:10.1016/s0041-1345(98)01663-7

Cited by 4 publications

(2 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The mean weight at the time of nephrectomy in the present donors was 70.9 kg and the mean baseline BMI was 26.5 kg/m 2 , respectively, comparable to those of the series of Samhan et al [5] and Textor et al [6] .…”

Section: Discussionsupporting

confidence: 86%

The effect of body mass index at the time of donation on postoperative and remote consequences of nephrectomy in 189 living-related kidney donors

Kerkeni

Rebaı̈

Bouzouita

et al. 2015

Arab Journal of Urology

View full text Add to dashboard Cite

ObjectiveTo analyse the effects of baseline body mass index (BMI) on the postoperative and remote consequences of nephrectomy in living kidney donors, as body weight is conventionally used as an exclusion criterion for kidney donation and a BMI of <35 kg/m2 is often required.Patients and methodsWe retrospectively studied 189 living-related kidney donors who had their nephrectomy between 1986 and 2009 in our urology department. We recorded the BMI at the time of donation, and analysed variables after surgery, and clinico-biological factors remotely. The effect of the initial BMI after surgery and much later after nephrectomy was assessed.ResultsThe mean follow-up was 9.28 years. The mean (range) BMI at the time of donation was 26.5 (18.5–41.1) kg/m2; 33% of donors were overweight (BMI 25–30) and 21% were obese (⩾30), with 10.5% having a BMI of >35 kg/m2. The duration of hospitalisation was not related to the BMI. There was no significant difference between the mean BMI of donors with a simple postoperative history and donors who had complications after surgery. Among obese donors, only 7.7% had a complication, which was a surgical-site infection in all cases. The baseline BMI was higher among donors who maintained normal renal function and no proteinuria than in donors with impaired renal function and/or proteinuria; the difference was not significant. The occurrence of hypertension or diabetes was independent of baseline BMI. Donors with dyslipidaemia had no significantly greater baseline BMI than those with no dyslipidaemia.ConclusionThe BMI at the time of kidney donation does not seem to influence the short- or long-term consequences of nephrectomy in living donors.

show abstract

Section: Discussionsupporting

confidence: 86%

The effect of body mass index at the time of donation on postoperative and remote consequences of nephrectomy in 189 living-related kidney donors

Kerkeni

Rebaı̈

Bouzouita

et al. 2015

Arab Journal of Urology

View full text Add to dashboard Cite

show abstract

“…Likewise, the mean levels of measured and estimated creatinine clearance follow the same pattern of improvement. Samhan and Omar, 1999 [10], studied the early changes in kidney function following live kidney donation. They reported an immediate and significant increase in effective renal plasma flow (ERPF) of the remaining kidney.…”

Section: Discussionmentioning

confidence: 99%

Long Term Prospective Assessment of Living Kidney Donors: Single Center Experience

et al. 2014

View full text Add to dashboard Cite

Virtually, all studies reporting the outcomes of living kidney donation beyond the first year from donation were retrospective. In this prospective study, the outcome of 81 consecutive living kidney donors was thoroughly evaluated. Clinical, laboratory, and radiological assessments were carried out at predonation (basal), 3, 6, 12, and 24 months after donation. The mean age at time of donation was 37.8 ± 9.8 years and the majority was females (75.3%). The mean BMI increased significantly after donation (P < 0.04). The mean serum creatinine levels (mg/dl) were 0.75 ± 0.14, 1.01 ± 0.22, 0.99 ± 0.21, 0.98 ± 0.20, and 0.94 ± 0.20 (P < 0.0001). Likewise, the mean levels of measured creatinine clearance (mL/min) were 148.8 ± 35.7, 94.7 ± 26.6, 95.5 ± 24.6, 96.7 ± 20.2, and 101.6 ± 26.2 (P < 0.0001). The mean 24 hours urinary protein excretion (gm/dL) were 0.09 ± 0.03, 0.19 ± 0.18, 0.16 ± 0.09, 0.18 ± 0.25, and 0.17 ± 0.12 (P < 0.0001). There were significant increases in the means of the longitudinal and transverse diameters of the remaining kidney over time (P < 0.001). Out of 42 female donors, eleven female donors have got successful postdonation pregnancies. There were no reported surgical complications, either intra- or postoperative. Long-term follow-up is necessary for all living kidney donors through local institutional and world registries. This trial is registered with ClinicalTrials.gov NCT00813579.

show abstract