Early auditory enrichment with music enhances auditory discrimination learning and alters NR2B protein expression in rat auditory cortex

Xu, Jinghong; Yu, Liping; Cai, Rui; Zhang, Ji Ping; Sun, Xinde

doi:10.1016/j.bbr.2008.07.018

Cited by 48 publications

(55 citation statements)

References 40 publications

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“…Prenatal auditory stimulation with either species-specific or complex rhythmic music sounds facilitated spatial learning when compared to unstimulated controls. Prenatal as well as postnatal auditory enrichment has been shown to enhance spatial learning and the neural substrates responsible for learning in the hippocampus of rats and mice [Kim et al, 2006;Xu et al, 2009]. In chicks, prenatal sound stimulation with either species-specific or music sounds significantly increased the expression of calcium binding proteins, neuronal size and mean synaptic density in the chick hippocampus and facilitated spatial learning at 12 h posthatch [Chaudhury et al, 2006[Chaudhury et al, , 2009[Chaudhury et al, , 2010.…”

Section: Discussionmentioning

confidence: 99%

Prenatal Complex Rhythmic Music Sound Stimulation Facilitates Postnatal Spatial Learning but Transiently Impairs Memory in the Domestic Chick

Kauser

Roy²,

Pal³

et al. 2011

Dev Neurosci

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Early experience has a profound influence on brain development, and the modulation of prenatal perceptual learning by external environmental stimuli has been shown in birds, rodents and mammals. In the present study, the effect of prenatal complex rhythmic music sound stimulation on postnatal spatial learning, memory and isolation stress was observed. Auditory stimulation with either music or species-specific sounds or no stimulation (control) was provided to separate sets of fertilized eggs from day 10 of incubation. Following hatching, the chicks at age 24, 72 and 120 h were tested on a T-maze for spatial learning and the memory of the learnt task was assessed 24 h after training. In the posthatch chicks at all ages, the plasma corticosterone levels were estimated following 10 min of isolation. The chicks of all ages in the three groups took less (p < 0.001) time to navigate the maze over the three trials thereby showing an improvement with training. In both sound-stimulated groups, the total time taken to reach the target decreased significantly (p < 0.01) in comparison to the unstimulated control group, indicating the facilitation of spatial learning. However, this decline was more at 24 h than at later posthatch ages. When tested for memory after 24 h of training, only the music-stimulated chicks at posthatch age 24 h took a significantly longer (p < 0.001) time to traverse the maze, suggesting a temporary impairment in their retention of the learnt task. In both sound-stimulated groups at 24 h, the plasma corticosterone levels were significantly decreased (p < 0.001) and increased thereafter at 72 h (p < 0.001) and 120 h which may contribute to the differential response in spatial learning. Thus, prenatal auditory stimulation with either species-specific or complex rhythmic music sounds facilitates spatial learning, though the music stimulation transiently impairs postnatal memory.

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Section: Discussionmentioning

confidence: 99%

Prenatal Complex Rhythmic Music Sound Stimulation Facilitates Postnatal Spatial Learning but Transiently Impairs Memory in the Domestic Chick

Kauser

Roy²,

Pal³

et al. 2011

Dev Neurosci

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“…It has been widely used as a therapeutic tool in many disorders in humans, for instance, Alzheimer disease (Simmons-Stern et al, 2010;Simmons-Stern et al, 2012), Parkinson disease (de Dreu et al, 2012), depression (Maratos et al, 2008), autistic spectrum disorder (Gold et al, 2006), schizophrenia (Mössler et al, 2011) and aphasia (van der Meulen et al, 2012). Using sensory enrichments, such as music, have been studied in several animals, including sheep, dairy cattle, piglets, goats, mice, rats, fish, horses, monkey and poultry, mainly day-old chicks (Uetake et al, 1997;Campo et al, 2005;de Jonge et al, 2008;Xu et al, 2009;Papoutsoglou et al, 2010;Stachurska et al, 2015;Xing et al, 2016). Although, using music is a vital tool for improving piglets and dairy cows' welfare and behaviour where it reduces the stress on cows and increases milk yield (O'Brein, 2014).…”

Section: Introductionmentioning

confidence: 99%

Effect of Using Two Music Types on Non-Pregnant Non-Lactating Arabi Ewes Behaviour As a Tool for Welfare Improvement

Meshabaz

Hussein

Mersham

et al. 2017

SJUOZ

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ABSTRACT:The present study was designed to determine whether playing two music types will improve behaviour of non-pregnant, nonlactating Arabi sheep. Thirty Arabi ewes, aged 2 -3 years, were included in the study. Ewes were divided into three groups, 10 ewes each. The groups were: Control (with no music exposure); Classic music exposure and Fast music exposure. The sound level for classic and fast music groups was 80 dB with the frequency of 1 KHz. The behavioural data were collected using direct observations for six respective days. Results revealed that using music, both classic and fast, significantly decreased the frequency of aggressive behaviours (P < 0.001), vocalization (P < 0.01), defecation (P < 0.05) and walking behaviour (P < 0.05). In addition, there were significant effects of music on the average time spent standing (P < 0.01), lying and feeding (P < 0.001). Whereas no significant difference was found on the average time spent drinking. It was shown that there were significant differences in time spent lying (P < 0.01) and time spent feeding (P < 0.01) over time. Finally, there was a significant difference in the proportion of time spent lying (P < 0.001) as well as in the proportion of time spent feeding between control and music groups (P < 0.01). From this study, it can be concluded that exposing non-pregnant, non-lactating ewes to classical music is beneficial for ewes' welfare, due to the reduction of aggressive behaviour.

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“…Previous work with domestic chicken embryos given musical enrichment prenatally showed increase in a variety of neurological factors associated with auditory function, increased plasticity, and neural survival (Alladi, Roy, Singh, & Wadhwa, 2005B;2005B;Chaudhury & Wadhwa, 2009;Wadhwa, Anand, & Bhowmick, 1998). Although there are practical limitations to providing auditory enrichment to mammals developing in-utero, studies of rats have found that prenatal auditory enrichment increases their performance on auditory discrimination tasks postnatally, even when those tasks consisted of stimuli outside of the range of the prenatal stimulation (Xu et al, 2009). In a rare study of prenatal auditory enrichment with human mothers and their fetuses, Blum (1998) found that a specific musical auditory-vestibular enrichment program influenced not only postnatal language development but also broader sensiomotor development.…”

Section: Discussionmentioning

confidence: 99%

“…However, the type of prenatal auditory enrichment was crucial; rats exposed to louder, mechanical sounds performed significantly poorer compared to controls and music enriched rats. Xu, Yu, Cai, Zhang, and Sun (2009) found that rats that received prenatal auditory enrichment in the form of music had altered levels of protein expression in the auditory nucleus that translated into significantly better performance in postnatal auditory discrimination tasks. The authors attribute the enriched rats' behavioral performance to increased neural plasticity.…”

Section: Enrichment Perceptual Narrowing and Response To Noveltymentioning

confidence: 99%

“…Table 1 Experiment 1 Hypotheses Experiment 2 investigated whether prenatal auditory enrichment could generalize to include stimuli that were not originally presented prenatally. Prenatal auditory enrichment has been shown to effect the underlying auditory neural architecture (Alladi, Roy, Singh, & Wadhwa, 2005A, 2005B;Chaudhury & Wadhwa, 2009;Wadhwa, Anand, & Bhowmick, 1998), decrease emotional reactivity (Kim et al, 2006), and improve performance in auditory discrimination tasks (Xu, Yu, Cai, Zhang, & Sun, 2009). …”

Section: Figurementioning

confidence: 99%

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The Effect of Prenatal Auditory Enrichment on Perceptual Narrowing in Bobwhite Quail Neonates

O'dowd¹

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Early auditory enrichment with music enhances auditory discrimination learning and alters NR2B protein expression in rat auditory cortex

Cited by 48 publications

References 40 publications

Prenatal Complex Rhythmic Music Sound Stimulation Facilitates Postnatal Spatial Learning but Transiently Impairs Memory in the Domestic Chick

Prenatal Complex Rhythmic Music Sound Stimulation Facilitates Postnatal Spatial Learning but Transiently Impairs Memory in the Domestic Chick

Effect of Using Two Music Types on Non-Pregnant Non-Lactating Arabi Ewes Behaviour As a Tool for Welfare Improvement

The Effect of Prenatal Auditory Enrichment on Perceptual Narrowing in Bobwhite Quail Neonates

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