Early and late angiographic findings of the “no-reflow” phenomenon following direct angioplasty as primary treatment for acute myocardial infarction

Feld, Harry; Lichstein, Edgar; Schachter, Jacob; Shani, Jacob

doi:10.1016/0002-8703(92)90520-6

Cited by 56 publications

(25 citation statements)

References 11 publications

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“…3) No-reflow phenomenon may lead to acute myocardial infarction and result in inhospital mortality. 4) Intracoronary administration of verapamil, 1) adenosine, 5) nicorandil, 6) papaverine, 7) urokinase, 8) or tissue-type plasminogen activator through the intravenous route 9) has been attempted to treat no-reflow phenomenon. However, none was found to promptly and effectively restore the coronary flow.…”

Section: Discussionmentioning

confidence: 99%

Restoration of Normal Coronary Flow With Tirofiban by Intracoronary Administration for No-reflow Phenomenon After Stent Deployment

et al. 2005

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SUMMARYNo-reflow phenomenon is frequently observed during percutaneous coronary intervention in patients with acute coronary syndrome. It may jeopardize hemodynamic status or result in ischemic chest pain in these patients. Currently, there is no adequate solution for this problem. We report our experience with an acute coronary syndrome patient who developed no-reflow phenomenon associated with ST segment elevation and shock after percuteneous coronary balloon dilatation and stent deployment. Intracoronary administration of tirofiban immediately restored the coronary flow of the target vessel, and the disastrous condition reversed. Our experience suggests that intracoronary administration of tirofiban can be considered as an option in case of no-reflow phenomenon during percutaneous coronary intervention. (Int Heart J 2005; 46: 139-145)

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Section: Discussionmentioning

confidence: 99%

Restoration of Normal Coronary Flow With Tirofiban by Intracoronary Administration for No-reflow Phenomenon After Stent Deployment

et al. 2005

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“…Intracoronary urokinase is ineffective. 126 Although various intravenous thrombolytic agents are beneficial in lysing thrombi, they do not appear to have a direct effect on the no-reflow phenomenon. 43,127 The no-reflow phenomenon is becoming increasingly recognized because of the spread of primary intervention for acute myocardial infarction and the emergence of contrast myocardial echocardiography.…”

Section: Managementmentioning

confidence: 99%

No-Reflow Phenomenon

2002

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“…Despite its numerous benefits, serious and potentially life-threatening complications of PCI can occur, including slow flow phenomenon, 1,2) and coronary dissection and perforation. 3,4) PCI, which depends upon mechanical dilatation of the artery or ablation of atherosclerotic plaque, is requisitely associated with plaque rupture, 5,6) plaque fracture, intimal splitting, localized media dissection, and frank perforation.…”

mentioning

confidence: 99%

Coronary Arterial Plaque Characterized by Multislice Computed Tomography Predicts Complications Following Coronary Intervention

Kinohira

Akutsu

et al. 2007

Int. Heart J.

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SUMMARYBackground: A reliable, noninvasive assessment of plaque configuration would constitute an important step forward for predicting complications following percutaneous coronary intervention (PCI). Multislice computed tomography (MSCT) holds promise with respect to allowing for differentiation of coronary lesion configuration. However, it has not yet been clarified whether the characteristics of coronary artery plaque measured by MSCT predict complications after PCI. The aim of this study was to investigate the relationship between plaque configuration and complications after coronary intervention in patients with stable angina pectoris.Methods: MSCT was performed in patients with angina pectoris who were scheduled for PCI prospectively, and 26 patients (70 ± 11 years, 18 males) with coronary artery plaque in a stenotic coronary artery measured by MSCT were recruited for this study. Thirty-five plaques in the stenotic coronary lesions were divided into 3 groups based on the CT density as soft, intermediate, and hard, and were compared with the complications after PCI. Results:The soft plaque group before PCI (n = 11) was significantly associated with the appearance of slow flow (n = 4) or a compromised side branch (n = 1) after PCI, whereas the hard plaque group before PCI (n = 17) was associated with the appearance of dissection (n = 2) or perforation (n = 1) after PCI (P = 0.004). The intermediate plaque group (n = 7) had only one complication, a compromised side branch (n = 1). Conclusion:Coronary arterial plaque characterized by MSCT can predict interventionrelated complication. It may be important for the risk stratification of the patients scheduled to undergo PCI to investigate plaque configuration by MSCT.(Int Heart J 2007; 48: [25][26][27][28][29][30][31][32][33]

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Early and late angiographic findings of the “no-reflow” phenomenon following direct angioplasty as primary treatment for acute myocardial infarction

Cited by 56 publications

References 11 publications

Restoration of Normal Coronary Flow With Tirofiban by Intracoronary Administration for No-reflow Phenomenon After Stent Deployment

Restoration of Normal Coronary Flow With Tirofiban by Intracoronary Administration for No-reflow Phenomenon After Stent Deployment

No-Reflow Phenomenon

Coronary Arterial Plaque Characterized by Multislice Computed Tomography Predicts Complications Following Coronary Intervention

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