Dysfunction of the peripheral and central auditory pathway in patients with type 1 diabetes mellitus

Fernandes, Luciene Chaves; Casais-Silva, Luciana; Ladeia, Ana Marice

doi:10.4236/jdm.2012.21012

Cited by 7 publications

(4 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is observed that the TEOAE recordings are not very frequency selective as compared to DPOAE. 10,11 In the present study, mean DPOAE SNR values for diabetics were lower in all frequencies [2000, 3000, 4000, 5000 and 6000 Hz] for diabetics. An early onset high frequency cochlear dysfunction in diabetics was indicated by lower SNR values with significant decrease for 4, 5 and 6 kHz.…”

Section: Discussionmentioning

confidence: 75%

A comparative study on effects of diabetes on auditory functions as measured by BERA and DPOAE

Joshi¹,

Galagali

Kanzhuly

et al. 2017

Int J Otorhinolaryngol Head Neck Surg

View full text Add to dashboard Cite

Background: Diabetes is prevalent endocrine disorder associated with many complications. However, the link between auditory dysfunctions and diabetes is still vague. The current study aims to correlate auditory dysfunction caused by DM, measured by distortion product otoacoustic emission (DPOAE) & brainstem evoked otoacoustic emissions (BERA). Methods: This is a descriptive (comparative) study in which auditory functions of 100 diabetics and 100 matched non-diabetics were assessed by distortion product otoacoustic emission (DPOAE) & brainstem evoked otoacoustic emissions (BERA). The data for diabetic and non- diabetic group was compared and analysed. Effects of age of individual on auditory functions were also analysed separately using suitable statistical tests. The data collected was analysed with suitable statistical tests were performed with a significance level of ɑ=0.1 using SPSS 2.0 software. Results: The demographical variable was comparable in both the groups. The results showed decline in free field hearing, which are further adversely affected by duration of diabetes and patient’s age. The pure tone thresholds were not significantly higher in diabetics; however the thresholds were significantly higher in diabetics in older age groups. The hearing loss appear at early age in diabetics but gradually become indistinguishable from age related hearing loss. Conclusions: Although the auditory dysfunction can be linked to diabetes, but are usually not detectable at earliest stages with routine clinical and audiological tests. The DPOAE and BERA have role to play in monitoring of the auditory dysfunction.

show abstract

Section: Discussionmentioning

confidence: 75%

A comparative study on effects of diabetes on auditory functions as measured by BERA and DPOAE

Joshi¹,

Galagali

Kanzhuly

et al. 2017

Int J Otorhinolaryngol Head Neck Surg

View full text Add to dashboard Cite

show abstract

“…Subclinical auditory alterations can only be detected with electrophysiological auditory tests – otoacoustic emission (OAE) and auditory brainstem response (ABR). Sensorial alterations can be distinguished with the OAE test, and neural alterations can be distinguished with the ABR test, which evaluates the auditory nerve and brainstem structures .…”

Section: Introductionmentioning

confidence: 99%

Dysfunction of the auditory system in sickle cell anaemia: a systematic review with meta‐analysis

Lago

Fernandes

Alves³

et al. 2019

Tropical Med Int Health

View full text Add to dashboard Cite

Objectives To describe the occurrence of both peripheral and central auditory system dysfunction in sickle cell anaemia (SCA) patients and discuss the different mechanisms hypothesised to be responsible for these alterations. Methods An electronic search was conducted using PubMed Central® (MEDLINE), LILACS® and Scopus® databases. This systematic review was performed in accordance with the PRISMA statement. Original observational studies that utilised audiological tests for auditory system evaluations in SCA were included. Results A total of 183 records were found in the databases searched. Twenty‐one of these studies met the inclusion criteria. Pooled prevalence of sensorineural hearing loss (SNHL) was 20.5% (CI: 10.3–33%). Retrocochlear involvement was detected with the auditory brainstem response, which assesses integrity of the cochlea, 8th cranial nerve and brainstem structures. In addition, the increase in otoacoustic emission amplitudes in SCA patients indicates changes in cochlear micromechanics and precedes the expression of a detectable cochlear pathology. Conclusion The prevalence of the SNHL is higher than in the general population. Dysfunction of the auditory system may be present in SCA patients, with the most probable mechanism being the presence of circulatory disturbances resulting from the chronic inflammatory state of the disease.

show abstract

“…Thus, T1DM may compromise the physiology of the inner ear at a subclinical level. In a previous literature review study, we investigated otoacoustic emissions, and a reduced amplitude was seen in patients with T1DM ( 18 ) . Histopathological findings of the inner ear of individuals with T1DM also favor this hypothesis, because they demonstrate the thickening of the capillary walls of the stria vascularis , the presence of hemorrhage and endolymphatic hydrops, a decreased number of fibers of the spiral blade, degenerative changes in the organ of Corti, and a reduction in external hair cells ( 3 ) .…”

Section: Discussionmentioning

confidence: 99%

Study of auditory pathways in type 1 diabetes mellitus through brainstem auditory evoked potentials and contralateral acoustic reflex

Fernandes

Andrade

Adan

et al. 2023

CoDAS

View full text Add to dashboard Cite

Purpose To investigate the functionalities of the neural pathways through the auditory evoked potentials of the brainstem and the contralateral stapedial acoustic reflexes in normal-hearing individuals with type 1 diabetes mellitus, in order to detect possible alterations in the central auditory pathways. Methods This is a cross-sectional study with a comparison group and a convenience sample, consisting of 32 individuals with type 1 diabetes mellitus and 20 controls without the disease. All subjects had hearing thresholds within normal limits and type A tympanometric curves. The acoustic reflex arc and brainstem auditory potentials were investigated. Statistical analyses were performed using the SPSS 17.0. The Chi-square test, Student´s t-test, and Multiple linear regression were used. Results The auditory thresholds of the acoustic reflex were statistically lower in the group with the disease at frequencies of 0.5 kHz and 1.0 kHz in the left ear (p=0.01 and p=0.01, respectively). The absolute latencies III and V of the auditory potentials of the brainstem in the right ear and V in the left ear were increased in subjects with type 1 diabetes mellitus (p=0.03, p=0.02 and p=0.03, respectively). Conclusion The findings suggest that subjects with type 1 diabetes mellitus are more likely to present alterations in the central auditory pathways, even with auditory thresholds within normal limits.

show abstract

Dysfunction of the peripheral and central auditory pathway in patients with type 1 diabetes mellitus

Cited by 7 publications

References 28 publications

A comparative study on effects of diabetes on auditory functions as measured by BERA and DPOAE

A comparative study on effects of diabetes on auditory functions as measured by BERA and DPOAE

Dysfunction of the auditory system in sickle cell anaemia: a systematic review with meta‐analysis

Study of auditory pathways in type 1 diabetes mellitus through brainstem auditory evoked potentials and contralateral acoustic reflex

Contact Info

Product

Resources

About