One of the main trends shaping the industry today is the development of application methods for various special coatings. Among a large number of coatings, retro-reflective coatings stand out: they are used in a variety of applications throughout the industry. The processes of retro-reflective surface forming have been studied rather thoroughly. The retro-reflective performance depends mainly on structural and optical properties, as well as properties of the radiation source itself. A method was developed to synthesize retro-reflective coatings with specified optical properties using the reflectors in the form of glass microspheres. Retro-reflective performance of the coatings was studied. The paper uses different approaches to microsphere packaging in the bonding layer. It was demonstrated that the half-widths of the scattering patterns of retro-reflective coatings with different structures were quite close, and the reflection maximum of the designed coatings approached the reflection maximum of the commercial “3M” film at the same allowable viewing angles.