Dynamics and metabolic profile of oral keratinocytes (NOK-si) and <i>Candida albicans</i> after interaction in co-culture

Masetti, Paula; Sanitá, Paula Volpato; Jorge, Janaína Habib

doi:10.1080/08927014.2021.1941908

Cited by 2 publications

(1 citation statement)

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“…Yeasts including Candida albicans can also be present in periodontal pockets in some periodontitis patients and Candida hyphae are reduced after periodontal scaling [ 38 ]. Candida albicans is a dimorphic yeast associated with tissue invasion and clinical infection that exists as blastoconidia, pseudohyphae, and hypha [ 39 ]. Cytokines such as IL-1b, IL-6, and IL-23 can be stimulated by Candida albicans , and induced the differentiation of Th17 cells with subsequent generation of IL-17 [ 40 ].…”

Section: Discussionmentioning

confidence: 99%

Synergistic Efficacy of Plaque Control with Intralesional Triamcinolone Acetonide Injection on Erosive Non-Gingival Oral Lichen Planus: A Randomized Controlled Clinical Trial

Zhao

Lin

Deng

et al. 2022

IJERPH

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This study is the first time to assess the synergistic efficacy and safety of plaque control on erosive non-gingival oral lichen planus (OLP). A randomized, controlled, clinical trial with blind evaluation was designed, and 48 OLP patients with erosive non-gingival OLP lesions were randomly assigned to the experimental group (n = 25, receiving intralesional triamcinolone acetonide injection, periodontal scaling, and oral hygiene instruction) and the control group (n = 23, only receiving intralesional triamcinolone acetonide injection) once a week for 2 weeks. Erosion size, pain level, plaque index, and community periodontal index were measured at every visit. Patients cured of erosion were followed up for 3 months to evaluate the recurrence rate. Adverse reactions were also recorded. At day 14 ± 2, the experimental group showed a higher completely healed percentage of erosion, a greater reduction of erosion size and pain level. However, no significant difference was observed in the recurrence rate. No participants had any severe adverse reactions. In conclusion, an improvement was observed in patients with plaque control, and future studies with larger sample sizes are needed to reinforce the external validity of this study.

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Section: Discussionmentioning

confidence: 99%