2021
DOI: 10.1038/s41598-021-87212-z
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Dynamic entropy of human blood

Abstract: Temperature control is a process that is used by biological systems to maintain a stable internal state for survival. People have an individually variable physiological temperature of about 36.6 °C, which can be modified by many undesirable factors. Based on an analysis of a time series of extracellular ionic fluxes that were obtained using the non-invasive solute-semiconductor interface technique, I show that this extremely specific (critical) temperature is encoded by a local minimum in the dynamic entropy o… Show more

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Cited by 9 publications
(4 citation statements)
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“…We also took the Slocombe et al 2 result on proton tunneling in the proton exchange between the nucleotide base pairs in DNA at room temperature as a given. Moreover, the low energy quantum tunneling of Cooper pairs as bosonic particles 23 can explain our experiments in which a zero bias peak was observed, which is in agreement with the profound minimum in the dynamic entropy 15 . Therefore, we hypothesized whether the ratio of the single protons (changing the level of the chemical potential, and hence, the pH of a system) to the paired protons (do not participate in pH-level) in the condensate might be responsible for the normal (canonical) and abnormal (tautomeric) mutations.…”
Section: Introductionsupporting
confidence: 88%
See 1 more Smart Citation
“…We also took the Slocombe et al 2 result on proton tunneling in the proton exchange between the nucleotide base pairs in DNA at room temperature as a given. Moreover, the low energy quantum tunneling of Cooper pairs as bosonic particles 23 can explain our experiments in which a zero bias peak was observed, which is in agreement with the profound minimum in the dynamic entropy 15 . Therefore, we hypothesized whether the ratio of the single protons (changing the level of the chemical potential, and hence, the pH of a system) to the paired protons (do not participate in pH-level) in the condensate might be responsible for the normal (canonical) and abnormal (tautomeric) mutations.…”
Section: Introductionsupporting
confidence: 88%
“…It was found that the concentration ratio between the canonical and tautomeric base pairs differs at and beyond criticality, respectively. The deviation of a cell (ion) system from a speci c temperature, at which entropy has a minimum 15 and critical pH occurs 16 , could be a source of the point mutations that lead to tautomerization.…”
Section: Introductionmentioning
confidence: 99%
“…The degree of interaction is quantified by a coupling parameter, also known as the inverse temperature. It has been observed that an increase in the inverse temperature parameter beyond a critical value induces the emergence of phase transitions in the system [23].…”
Section: Introductionmentioning
confidence: 99%
“…We proposed a similar contact method to determine the level of chemical potential in the soft matter for the ion oscillations of a single (living) cell using the n-type semiconductor-electrolyte interface 2 . The latter also enabled the localization of the characteristic temperature of individually variable human peripheral blood and the detection of non-equilibrium phase transition 4,5 , respectively. In this article, we verify and confirm the existence of a noise-induced (or -detected) non-equilibrium phase transition 14 experimentally in a, generating ionic fluxes, ensemble of pollen tubes.…”
mentioning
confidence: 99%