Dynamic Chest CT Evaluation in Three Cases of 2019 Novel Coronavirus Pneumonia

Chen, Xing; Liu, Shuying; Zhang, Chunyi; Pu, Guimei; Sun, Jian; Shen, Juxin; Chen, Yefeng

doi:10.34172/aim.2020.11

Cited by 10 publications

(10 citation statements)

References 17 publications

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“…In the included studies, the mean time between initial chest CT and follow-up was about 6.5 days (range, 0–21 days). According to the report of 9 included studies, 43% (95 CI: 26%–61%) patients have improved follow-up chest CT findings, while 30% (95 CI: 18%–46%) have advanced chest CT findings [ 40 , 43 , 44 , 50 , 52 , 57 , 64 – 66 ]. Our findings demonstrated pure ground-glass opacity in early disease, followed by the development of crazy paving, and finally increasing consolidation latter in the disease course.…”

Section: Resultsmentioning

confidence: 99%

Computed Tomography (CT) Imaging Features of Patients with COVID-19: Systematic Review and Meta-Analysis

Awulachew

Diriba

Anja

et al. 2020

Radiology Research and Practice

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Introduction. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious disease, and its first outbreak was reported in Wuhan, China. A coronavirus disease (COVID-19) causes severe respiratory distress (ARDS). Due to the primary involvement of the respiratory system, chest CT is strongly recommended in suspected COVID-19 cases, for both initial evaluation and follow-up. Objective. The aim of this review was to systematically analyze the existing literature on CT imaging features of patients with COVID-19 pneumonia. Methods. A systematic search was conducted on PubMed, Embase, Cochrane Library, Open Access Journals (OAJ), and Google Scholar databases until April 15, 2020. All articles with a report of CT findings in COVID-19 patients published in English from the onset of COVID-19 outbreak to April 20, 2020, were included in the study. Result. From a total of 5041 COVID-19-infected patients, about 98% (4940/5041) had abnormalities in chest CT, while about 2% have normal chest CT findings. Among COVID-19 patients with abnormal chest CT findings, 80% (3952/4940) had bilateral lung involvement. Ground-glass opacity (GGO) and mixed GGO with consolidation were observed in 2482 (65%) and 768 (18%) patients, respectively. Consolidations were detected in 1259 (22%) patients with COVID-19 pneumonia. CT images also showed interlobular septal thickening in about 691 (27%) patients. Conclusion. Frequent involvement of bilateral lung infections, ground-glass opacities, consolidation, crazy paving pattern, air bronchogram signs, and intralobular septal thickening were common CT imaging features of patients with COVID-19 pneumonia.

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Section: Resultsmentioning

confidence: 99%

Computed Tomography (CT) Imaging Features of Patients with COVID-19: Systematic Review and Meta-Analysis

Awulachew

Diriba

Anja

et al. 2020

Radiology Research and Practice

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“…Findings on chest radiograph imaging are not diseasespecific and usually include ground glass opacities with bilateral, peripheral or lower lung zone distribution with or without consolidation [21][22][23]. Chest CT is more sensitive, but no finding can 100% establish or rule out the diagnosis [24].…”

Section: Pulmonary Involvementmentioning

confidence: 99%

Organ-specific manifestations of COVID-19 infection

et al. 2020

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Although COVID-19 presents primarily as a lower respiratory tract infection transmitted via air droplets, increasing data suggest multiorgan involvement in patients that are infected. This systemic involvement is postulated to be mainly related to the SARS-CoV-2 virus binding on angiotensin-converting enzyme 2 (ACE2) receptors located on several different human cells. Lung involvement is the most common serious manifestation of the disease, ranging from asymptomatic disease or mild pneumonia, to severe disease associated with hypoxia, critical disease associated with shock, respiratory failure and multiorgan failure or death. Among patients with COVID-19, underlying cardiovascular comorbidities including hypertension, diabetes and especially cardiovascular disease, has been associated with adverse outcomes, whereas the emergence of cardiovascular complications, including myocardial injury, heart failure and arrhythmias, has been associated with poor survival. Gastrointestinal symptoms are also frequently encountered and may persist for several days. Haematological complications are frequent as well and have been associated with poor prognosis. Furthermore, recent studies have reported that over a third of infected patients develop a broad spectrum of neurological symptoms affecting the central nervous system, peripheral nervous system and skeletal muscles, including anosmia and ageusia. The skin, the kidneys, the liver, the endocrine organs and the eyes are also affected by the systemic COVID-19 disease. Herein, we provide a comprehensive overview of the organ-specific systemic manifestations of COVID-19.

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“…Diffuse damage, edema, and transparent membrane formation of the lungs after the invasion are complications of COVID-19 infection, which is similar to pathological changes caused by SARS and MERS [4]. Zhou S et al [5] have attributed the peripheral distribution of COVID-19 lesions to virus invasion of bronchioles and alveoli, causing inflammatory reactions which need the participation of immune cells, and added that the distribution of blood vessels and lymphatics rich in immune cells is more abundant in the peripheral and lower areas.…”

Section: Introductionmentioning

confidence: 82%

COVID-19 CT Features: A Scoping Literature Review

Babiker¹

2020

SJAMS

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Dynamic Chest CT Evaluation in Three Cases of 2019 Novel Coronavirus Pneumonia

Cited by 10 publications

References 17 publications

Computed Tomography (CT) Imaging Features of Patients with COVID-19: Systematic Review and Meta-Analysis

Computed Tomography (CT) Imaging Features of Patients with COVID-19: Systematic Review and Meta-Analysis

Organ-specific manifestations of COVID-19 infection

COVID-19 CT Features: A Scoping Literature Review

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