1991
DOI: 10.1016/0002-8703(91)90675-8
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Dynamic changes in left ventricular outflow tract flow velocities after amyl nitrite inhalation in hypertrophic cardiomyopathy

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Cited by 26 publications
(9 citation statements)
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“…Asym metrical hypertrophy, diastolic dysfunction and the dynamic LVOT gradient as the essen tial abnormalities are now readily detectable by cardiac ultrasound [14][15][16][17][18][19][20]. Markedly in creased outflow velocities localized within the LV cavity at rest or with provocation [15,19,21] have been found to represent the LVOT gradient. By the typical, late-peaking flow pro file [19] distinction of dynamic from both fixed LVOT obstruction, as in valvular aortic stenosis, and from mitral regurgitation is pos sible.…”
Section: Discussionmentioning
confidence: 99%
“…Asym metrical hypertrophy, diastolic dysfunction and the dynamic LVOT gradient as the essen tial abnormalities are now readily detectable by cardiac ultrasound [14][15][16][17][18][19][20]. Markedly in creased outflow velocities localized within the LV cavity at rest or with provocation [15,19,21] have been found to represent the LVOT gradient. By the typical, late-peaking flow pro file [19] distinction of dynamic from both fixed LVOT obstruction, as in valvular aortic stenosis, and from mitral regurgitation is pos sible.…”
Section: Discussionmentioning
confidence: 99%
“…Hypovolemia and inotropic or β-adrenergic stimulation should be avoided in affected patients [36, 37]. Problems may arise in patients displaying acute signs of cardiac failure and cardiopulmonary polymorbidity.…”
Section: Discussionmentioning
confidence: 99%
“…The increase of heart rate was similar during both provocation maneuvers. Even the application of short-acting amylnitrite may induce palpitations and mild light-headedness [13]. As compared with the tilt table test, another disadvantage of amylnitrite may be the short observation time of only 20 to 30 seconds.…”
Section: Discussionmentioning
confidence: 99%