Duodenal Metastases From Renal Cell Carcinoma Presented With Melena: Review and Case Report

Omranipour, Ramesh; H, Mahmoud Zadeh; Ensani, Fereshteh; Yadegari, Samira; Miri,

doi:10.30699/ijp.2017.25687

Cited by 8 publications

(7 citation statements)

References 19 publications

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“…In general, 4% of RCC metastasises to the gastrointestinal tract. Metastasis to the duodenum is reported in 25 cases only with an incidence rate of 0.2% and 0.7% having gastrointestinal haemorrhage or obstruction (as reported in our case) as the most common clinical presentation [8]. Metastasis of RCC to the duodenum occurs via lymphatic and haematogenous spread usually or by direct infiltration; what may explain the duodenal involvement from the recurrent mass in the right nephrectomy bed in this case [9].…”

Section: Discussionsupporting

confidence: 53%

Synchronous invasive ductal carcinoma of the breast and clear cell renal carcinoma with rare presentation and behaviour: a case report with a literature review

Hassan

Fakhrudiin

Farhat

2020

ecancer

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The presence of two or more primary tumours is a relatively uncommon phenomenon. Recently with the improvement of diagnostic modalities, such cases are increasingly reported in the literature. This paper presents a rare case of synchronous breast and renal tumour with unusual features including RCC metastasis to the duodenum and stomach, rapid recurrence of the tumour at the nephrectomy site, rapid renal cell carcinoma growth rate and the rare presence of syncytial-type giant cells in the renal cell tumour.

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Section: Discussionsupporting

confidence: 53%

Synchronous invasive ductal carcinoma of the breast and clear cell renal carcinoma with rare presentation and behaviour: a case report with a literature review

Hassan

Fakhrudiin

Farhat

2020

ecancer

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“…This is of particular concern given a significant number of these patients require anticoagulation for malignancy-related thromboembolic events [6]. Additionally, cases of obstruction, perforation, intussusception and obstructive jaundice secondary to duodenal metastases from RCC have been reported [7]. On direct visualisation by endoscopy lesions are mostly solitary, polypoid or ulcerated submucosal masses [4].…”

Section: Discussionmentioning

confidence: 99%

An Unusual Case of Gastrointestinal Bleeding in Metastatic Renal Cell Carcinoma

2020

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Approximately 340 patients are diagnosed with renal cell cancer (RCC) in Ireland each year. Metastatic spread to the lung, lymph nodes and bones is common. Metastatic spread to the gastrointestinal tract, including the small bowel, is a rare phenomenon. Therapeutic advances have led to an improved overall survival in RCC and, as a result, unusual sites of metastatic spread are becoming more common. We present the case of a 68-year-old gentleman presenting with upper gastrointestinal bleeding as a result of metastases to the duodenum from renal cell carcinoma.

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“…Recurrence of tumors at typical sites decreased, whereas retroperitoneal organ recurrence increased in a time-dependent manner, with a pancreatic metastatic rate of 2.7% (3). A periampullary metastasis from an RCC is reported to be sporadic, which is found only in 19 cases, including the present one (4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19). Perambulator metastases ordinarily emerges acute or chronic gastrointestinal hemorrhage (13/19), duodenal obstruction (4/19), duodenal ulcer (1/19), or obstructive jaundice (1/19).…”

Section: Discussionmentioning

confidence: 73%

A case report of the pancreatic and periampullary metastases of renal cell carcinoma, 17 years after surgery

Lu¹,

Ying²,

Zhu³

et al. 2021

Transl Cancer Res TCR

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Renal cell carcinoma (RCC) is the most common renal tumor with a high incidence in the recent decade. Generally, an RCC metastasis mainly occurs via hematogenous and lymphomatous routes.Even though RCC has a potential to metastasize to almost any site, metastasis to the pancreas and duodenal ampulla is a rare event. In this study, we describe a case of pancreatic and periampullary metastatic renal cell carcinoma, which recurred 17 years after surgery. The patient admitted to hospital for severe symptoms of jaundice and skin pruritus after removal of the primary tumor for 17 years. Computer tomography angiography (CTA) scan and endoscopy showed pancreatic and duodenal ampullary metastasis. Finally, it confirmed by histopathologic examination. After some symptomatic treatment has been given the patient remained alive. However, intermittent hematochezia along with these metastatic lesions continue to occur until now as observed during the annual follow-up appointments. This study concludes that metastatic involvement of the pancreas and other organs should be suspected in any patient with a history of an RCC who does not manifest any typical symptom even after more than 10 years of RCC resection. In the case of abnormal symptoms and examination results after several years of RCC surgery, attention should be paid to provide immediate treatment.

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Duodenal Metastases From Renal Cell Carcinoma Presented With Melena: Review and Case Report

Cited by 8 publications

References 19 publications

Synchronous invasive ductal carcinoma of the breast and clear cell renal carcinoma with rare presentation and behaviour: a case report with a literature review

Synchronous invasive ductal carcinoma of the breast and clear cell renal carcinoma with rare presentation and behaviour: a case report with a literature review

An Unusual Case of Gastrointestinal Bleeding in Metastatic Renal Cell Carcinoma

A case report of the pancreatic and periampullary metastases of renal cell carcinoma, 17 years after surgery

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