Abstract:Analysis of engagement of serotonin-modulating anticonsolidation protein (SMAP) in formation of drug addiction to morphine in self-administration model in the rats via application of the anti-SMAP antibodies
MethodsIndirect ELISA-test, morphine self-administration model, conditioned model of alternative running, conditioned model of instrumental differentiation.
ResultsUpregulation of SMAP by 67% in the brain cingulate cortex of the rats with stable level of morphine intake, while no changes of SMAP level were… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.