Dual-site fluorescent probe for bioimaging of upregulated adenosine triphosphate under the stresses of endogenous and exogenous H2S

A COX2-targeting cancer-specific fluorescent probe for hydrogen sulfide detection in living cells, Caenorhabditis elegans, and zebrafish

“…11 In this regard, many fluorescent probes specific for H 2 S detection have been developed. [12][13][14][15][16][17][18][19][20][21] In our previous work, a H 2 S triggered twophoton ratiometric fluorescent theranostic probe was also designed and studied in vitro and in vivo. 22 Unfortunately, these probes failed to differentiate tumor tissues from normal tissues, which is a considerable limitation for clinical application.…”

Robust Optical Detection of Ga3+ by a Rhodamine- and Coumarin-Based Proficient Probe: Theoretical Investigations and Biological Applications

“…Rhodamine-B is a well-known fluorescent dye used in the detection of metal ions, and coumarin derivatives are renowned for their extensive fluorescence properties. Rhodamine-based chemosensors can easily detect their targeted analytes due to their convenient close–open ring structure. − The detected analyte becomes very sensitive to the probe in terms of its multiple-fold increment in intensity. This is due to the spiro structure of the probe, which causes spirolactam ring opening in the presence of targeted analytes and proclaims the colorimetric and/or fluorescent reactions .…”

A tracer-type fluorescent probe for imaging adenosine triphosphate under the stresses of hydrogen sulfide and hydrogen peroxide in living cells

“…[14][15][16][17][18][19] However, in recent decades, there have only been a few reports on small-molecule fluorescent probes for ATP detection, mainly through the opening of the spirolactam in rhodamine to release fluorescence for simple identification. [20][21][22][23][24] More importantly, few probes have been reported that can simultaneously recognize ATP and track the probe to improve detection accuracy. [25][26][27] Therefore, the design of highly selective and sensitive ATP detection probes is still an urgent problem to be solved.…”