Dual excitable upconversion nanoparticle@polydopamine nanocomposite with intense red emission and efficient photothermal generation

Liao, Huazhen; Ye, Song; Xu, Xinling; Lin, Peixuan; Pan, Ling; Wang, Deping

doi:10.1016/j.jre.2022.12.008

Cited by 3 publications

(2 citation statements)

References 49 publications

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“…243 In addition, some of the UCNPs can also be used as photothermal agents. 244 In conclusion, despite the low upconversion efficiency and the lack of cell-type-specific targeting capability, UCNPs still pave the way for novel photostimulation in neuromodulation. 245…”

Section: Upconversion Nanoparticle-mediated Light Stimulationmentioning

confidence: 98%

Functional material-mediated wireless physical stimulation for neuro-modulation and regeneration

Li,

Wu,

Zeng

et al. 2023

J. Mater. Chem. B

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Section: Upconversion Nanoparticle-mediated Light Stimulationmentioning

confidence: 98%

Functional material-mediated wireless physical stimulation for neuro-modulation and regeneration

Li,

Wu,

Zeng

et al. 2023

J. Mater. Chem. B

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“…Moreover, an appropriate increase in temperature caused by photothermal materials can be used to kill tumor cells. [31][32][33][34][35][36][37] WZB117 is believed to inhibit the energy gain of tumor cells, thereby suppressing the expression of heat shock proteins 90 (HSP90) and enhancing the photothermal killing effect of tumor cells. [38,39] In this study, we first synthesized Pd@CeO 2 with a coreshell structure.…”

Section: Introductionmentioning

confidence: 99%

Engineering Nanozymes for Tumor Therapy via Ferroptosis Self‐Amplification

Liu,

Wei,

Liang

et al. 2024

Adv Healthcare Materials

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Ferroptosis induction is an emerging strategy for tumor therapy. Reactive oxygen species (ROS) can induce ferroptosis but are easily consumed by overexpressed glutathione (GSH) in tumor cells. Therefore, achieving a large amount of ROS production in tumor cells without being consumed is key to efficiently inducing ferroptosis. In this study, we designed a self‐amplifying ferroptosis‐inducing therapeutic agent, Pd@CeO2‐Fe‐Co‐WZB117‐DSPE‐PEG‐FA (PCDWD), for tumor therapy. PCDWD exhibits excellent multi‐enzyme activities due to the loading of Fe‐Co dual atoms with abundant active sites, including peroxidase‐like enzymes, catalase‐like enzymes, and glutathione oxidases, which undergo catalytic reactions in the tumor microenvironment to produce ROS, thereby inducing ferroptosis. Furthermore, PCDWD can also deplete GSH in tumor cells, thus reducing the consumption of ROS by GSH and inhibiting the expression of glutathione peroxidase 4. Moreover, the photothermal effect of PCDWD can not only directly kill tumor cells but also further enhance its own enzyme activities, consequently promoting ferroptosis in tumor cells. In addition, WZB117 can reduce the expression of heat shock protein 90 by inhibiting glucose transport, thereby reducing the thermal resistance of tumor cells and further improving the therapeutic effect. Finally, X‐ray computed tomography imaging of PCDWD guide it to achieve efficient tumor therapy.This article is protected by copyright. All rights reserved

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Controllable chemical synthesis of core-shell NaGdF4:Yb3+/Er3+@Bi4O5I2/Bi5O7I Z-scheme heterojunction for efficient tetracycline hydrochloride photodegradation

Wu,

Xue,

Cao

et al. 2024

Journal of Alloys and Compounds

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Dual excitable upconversion nanoparticle@polydopamine nanocomposite with intense red emission and efficient photothermal generation

Cited by 3 publications

References 49 publications

Functional material-mediated wireless physical stimulation for neuro-modulation and regeneration

Functional material-mediated wireless physical stimulation for neuro-modulation and regeneration

Engineering Nanozymes for Tumor Therapy via Ferroptosis Self‐Amplification

Controllable chemical synthesis of core-shell NaGdF4:Yb3+/Er3+@Bi4O5I2/Bi5O7I Z-scheme heterojunction for efficient tetracycline hydrochloride photodegradation

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