Dual Energy CT – eine neue Perspektive in der Gicht-Diagnostik

Abstract

DECT allows specific and quantitative visualization of urate deposits in peripheral regions. Taking into account the amount of urate deposits shown in DECT, the diagnosis of gout can be stated reliably. Based on our experience and results, DECT greatly benefits the routine diagnosis of gout in peripheral regions.

Diagnostic Value of Clinical, Laboratory, and Imaging Findings in Patients with a Clinical Suspicion of Gout: A Systematic Literature Review

“…Eight meeting abstracts were selected, but all were excluded after detailed review. Included studies [7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26] . Details on the popula-tion and index tests of the 19 included studies are available in Table 1 (reference standard is MSU crystals) and Appendixes 5 and 6 available online (other reference standards also available) from http:/www.3egout.com.…”

“…Details on the popula-tion and index tests of the 19 included studies are available in Table 1 (reference standard is MSU crystals) and Appendixes 5 and 6 available online (other reference standards also available) from http:/www.3egout.com. Overall, included studies were considered of a low 11 , unclear 14,16 , or high 7,8,9,10,13,15,[17][18][19][20][21][21][22][23][24][25][26] risk of bias (see Appendix 5, available from http:/www.3egout.com). Four studies (5 articles) used MSU crystal identification as their reference standard 11,14,16,26 (currently the best available reference standard).…”

Gicht – die „vergessene” Erkrankung trotz vieler therapeutischer Optionen

“…Mittelfußarthritis) zum Einsatz kommen. Eine neuere Entwicklung in der Bildgebung stellt das sogenannte "Dual Energy"-CT dar, hiermit können bereits sehr spezifisch frühe Kristallablagerungen nachgewiesen werden [2]. Im klinischen Alltag kann der Gelenkultraschall ebenfalls bereits frühe Kristallablagerungen zeigen und erweist sich außerdem vor der anzustrebenden Gelenkpunktion als hilfreich.…”

Difficult diagnosis of gout: the benefit of dual energy computed tomography, initial experience in routine clinical practice

“…6 Generally, DECT is able to detect very small-sized crystal deposits, but interestingly only deposits >2 mm in size are causing symptoms. 7 The quantification of tissue urate burden with dual energy CT during urate lowering therapy may help monitoring the success of the initiated urate lowering therapy. 8 There is evidence that DECT can serve as a problem-solving tool in the presence of challenging clinical presentations.…”