“…The low percentage of female drug users in this study is consistent with findings from other research on drug users [ 16 , 18 , 27 , 28 ]. This has been related to socioeconomic and cultural variables.…”
Introduction
Hepatitis B virus infection poses a global health challenge, particularly in low- and middle-income African countries. Illicit drug use exacerbates the problem, with drug users having a higher HBV infection risk and maintaining a quiet transmission pool. This study aimed to determine HBV infection prevalence, immune status, and risk factors among illegal drug users in Enugu State, Nigeria.
Materials and methods
A cross-sectional study was conducted in Enugu State, using privileged access interviewer methods to enroll drug users. Pre-tested structured questionnaires were administered after informed consent was obtained. Blood samples were tested for HBsAg, HBsAb, HBeAg, HBeAb, and HBcAb using immunochromatographic rapid test kits. Statistical analysis was performed using SPSS version 25.
Results
One hundred drug users were recruited into the study. Overall, 7% of the drug users had HBV infection. 61% were found to be susceptible to HBV infection, 15% showed serological evidence of immunity from HBV vaccination and 1% developed natural immunity from HBV exposure. Significant risk factors for HBV infection were age less than 20 years, young age (≤ 20 years) at drug initiation, being single, injecting drugs more than or equal to 20 times per month and injecting with used syringes.
Conclusion
This study shows high intermediate endemicity of HBV infection among drug users, low vaccination uptake, and high susceptibility to HBV infection. This calls for the urgent inclusion of drug users in national HBV vaccination campaigns and the adoption of the World Health Organization’s recommendations on the prevention of viral hepatitis among people who inject drugs.
“…The low percentage of female drug users in this study is consistent with findings from other research on drug users [ 16 , 18 , 27 , 28 ]. This has been related to socioeconomic and cultural variables.…”
Introduction
Hepatitis B virus infection poses a global health challenge, particularly in low- and middle-income African countries. Illicit drug use exacerbates the problem, with drug users having a higher HBV infection risk and maintaining a quiet transmission pool. This study aimed to determine HBV infection prevalence, immune status, and risk factors among illegal drug users in Enugu State, Nigeria.
Materials and methods
A cross-sectional study was conducted in Enugu State, using privileged access interviewer methods to enroll drug users. Pre-tested structured questionnaires were administered after informed consent was obtained. Blood samples were tested for HBsAg, HBsAb, HBeAg, HBeAb, and HBcAb using immunochromatographic rapid test kits. Statistical analysis was performed using SPSS version 25.
Results
One hundred drug users were recruited into the study. Overall, 7% of the drug users had HBV infection. 61% were found to be susceptible to HBV infection, 15% showed serological evidence of immunity from HBV vaccination and 1% developed natural immunity from HBV exposure. Significant risk factors for HBV infection were age less than 20 years, young age (≤ 20 years) at drug initiation, being single, injecting drugs more than or equal to 20 times per month and injecting with used syringes.
Conclusion
This study shows high intermediate endemicity of HBV infection among drug users, low vaccination uptake, and high susceptibility to HBV infection. This calls for the urgent inclusion of drug users in national HBV vaccination campaigns and the adoption of the World Health Organization’s recommendations on the prevention of viral hepatitis among people who inject drugs.
“…Two other barriers to care that emerged in the literature were gender, with women consistently accessing SUD treatment at lower rates [ 22 – 24 , 26 , 34 , 36 – 39 ] and linguistic and ethnic discordance between treatment-seekers and providers [ 38 , 39 ]. A general lack of availability of services was attributed to multiple factors, including a paucity of investment on the part of regional and national governments [ 40 , 42 , 43 , 45 ].…”
Section: Discussionmentioning
confidence: 99%
“…In a study from a psychiatric hospital in the Gambia, more than one-third of the sample population (35%) met the diagnostic criteria for a psychiatric or mood disorder in addition to SUD [ 21 ]. Many of the studies included in this review from Nigeria were conducted in a neuropsychiatric facility [ 18 , 19 , 25 , 26 ], and researchers noted that the location of SUD treatment in psychiatric facilities may contribute to low uptake of SUD services [ 26 ].…”
Section: Treatment Demand and Accessmentioning
confidence: 99%
“…Analysis of the literature indicates that men in Kenya likely access residential and inpatient SUD services at higher rates than women, as men were a greater proportion of participants in all of the sample populations in studies from Kenya that reported the demographic information [ 22 , 24 , 34 ]. In Nigeria, one study noted the overrepresentation of men in the sample population, who accounted for over 90% of patients in treatment while over a quarter of people who use drugs (PWUD) in Nigeria are women [ 26 ].…”
Background
With substance use rates increasing in Sub-Saharan Africa (SSA), an understanding of the accessibility and effectiveness of rehabilitative services for people who use alcohol and other drugs (AOD) is critical in the global efforts to diagnose and treat substance use disorders (SUD). This scoping review seeks to address the gaps in knowledge related to the types of research that have been conducted regarding inpatient or residential SUD treatment in SSA, the settings in which the research was conducted, and the study countries.
Methods
A search of three databases, PubMED, Scopus, and African Index Medicus, was conducted for publications related to the treatment of SUD in inpatient or residential settings in SSA. Articles were screened at the title/abstract level and at full text by two reviewers. Articles eligible for inclusion were original research, conducted in SSA, published in English, included populations who received or were currently receiving treatment for SUD in inpatient or residential settings, or documented demand for SUD services.
Results
This scoping review included 82 studies originating from 6 countries in SSA. Three themes emerged within the literature: access and demand for inpatient and residential SUD treatment, quality and outcomes of SUD treatment, and descriptions of the services offered and staffing of these facilities. Barriers to access include financial barriers, limited availability of services, and geographic concentration in cities. Women were shown to access residential and inpatient SUD treatment at lower rates than men, and certain racial groups face unique language and financial barriers in accessing services. Studies indicate mixed success of inpatient and residential SUD treatment in sustained SUD remission for patients.
Conclusion
There are significant gaps in the literature, driven by a lack of longitudinal studies focused on patient outcomes following treatment and the use of a narrow definition of treatment success. Both structural and non-structural barriers, such as stigma and discrimination, are barriers to access. Further research is needed to evaluate approaches to mitigate these barriers and expand access to residential and inpatient SUD treatment.
“…The consumption of psychoactive substances is an agelong phenomenon. In all known history and culture, psychoactive substances like alcohol and kola nuts, among others, have been in use for several reasons: energizers, elevation of mood, reduction of hunger, stress, and anxiety (James, 2019). Drug abuse, also known as substance abuse, is a pattern of drug use in which the user consumes drugs in amounts or methods that are harmful to themselves or others.…”
The study on parenthood and drug abuse among young people in Andoni Local Government Area, Rivers State, was motivated by the uncontrollable use of illicit drugs, alcoholism, and other controlled drugs, as well as their manifestations in crime, moral decay, health issues, poor academic interest, and a high social life. The study used a descriptive, cross-sectional research design. The required data was collected using a structured questionnaire, with a sample size of 440 and a multistage sampling method. The findings revealed a connection between teenage drug abuse in Andoni L.G.A. of Rivers State and the manner of parenting. The findings showed that among young people with good parentage, drug abuse was related to 88 (32.2%) of them, while drug abuse was also connected to 38 (28.5%) of those with bad parentage. Accordingly, the findings imply a connection between good parenting and the high prevalence of drug usage among young people in Andoni L.G.A., Rivers State. The study came to the conclusion that these findings highlight the intricate interaction of factors influencing young people's behaviour and demand an all-encompassing strategy to address substance addiction issues in this group.
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