Drug prescribing patterns for outpatients in three hospitals in north-west Ethiopia

Desta, Zeruesenay; Abula, Teferra; Gebre-Yohannes, Asfawoseen; Worku, Alemayehu

doi:10.4314/ejhd.v16i2.9809

Cited by 30 publications

(27 citation statements)

References 5 publications

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“…27% in Kuwait (19) and 15-46% in the Gambia (19). The low prevalence in this study may be attributed to differences in study area, subjects, sample size or elimination of H. pylori infection as a result of antibiotic treatment in occasion of concomitant diseases, such as giardiasis, amoebiasis, and respiratory diseases, etc., as these diseases are reported to be more prevalent in the study area (22). In this study, there were no statistically significant differences between dyspeptics and non-dyspeptics in the frequency of detection of H. pylori by serological methods, which is in agreement with the results obtained from other studies (23)(24)(25).…”

Section: Discussionsupporting

confidence: 93%

Serioprevalence of <i>Helicobacter pylori</i> Infection in and its Relationship with ABO Blood Groups

Tadege¹,

Mengistu²,

Desta³

et al. 2005

Ethiopian Journal of Health Development

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Background: Helicobacter pylori infection occurs worldwide, but the prevalence varies greatly among countries and among population groups studied. People with blood group O have been noted to be more susceptible to H. pylori infection. Objectives: To determine the magnitude of H. pylori infection in adult patients with and without dyspeptic symptoms attending Felege Hiwot Hospital, Bahir Dar, North West Ethiopia. We also prospectively examined the relationship between H. pylori infection and ABO blood groups in those subjects to clarify the possible association. Methods: A case-control study was conducted between dyspeptic (n=100) and non-dyspeptic patients (n=100) for the presence of H. pylori infection between mid November 2002 and March 2003 by using serology. Results: Of the total 200 subjects, 128 (64%) were males and 72 (36%) females with mean age of 32.7, range 15-75, years. Of these, 112 (56%) and 66 (33%) were found positive and negative for H. pylori infection, respectively, by EIA. Borderline values were measured in 22/200 (11%). H. pylori infection was detected in 124/200 (62%) of study subjects by immunoblot. The most prevalent blood group was type O (43%), followed by A (23.5%), B (22.5%) and AB (11%). In comparison of the subjects with blood group O and the other blood groups, no statistical significance could be identified in the seroprevalence of H. pylori ( p>0.05). Conclusion:The overall seroprevalence of H. pylori infection in Bahir Dar in this study was between 63% and 70% in dyspeptic patents and 49% and 54% in non-dyspeptic patients by EIA and IB, respectively. There were no statistically significant differences in the frequency of H. pylori seroprevalence between dyspeptic and non-dyspeptic patients. There was no statistically significant association between H. pylori infection and sex, age and ABO blood groups. Thus, further investigations along this line are recommended. [Ethiop.J.Health Dev. 2005;19(1):55-59]

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Section: Discussionsupporting

confidence: 93%

Serioprevalence of <i>Helicobacter pylori</i> Infection in and its Relationship with ABO Blood Groups

Tadege¹,

Mengistu²,

Desta³

et al. 2005

Ethiopian Journal of Health Development

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“…However, other studies conducted in different parts of Ethiopia showed that the use of generic products (Bahirdar hospitals 70.5%, Gonder hospital 72.6% and Debretabore hospital 84%) was low compared to this study showing the better performance of the present study hospital in this regard. 11 Lastly, this study found that poly pharmacy was common and found in 28.3% of patients. This magnitude is higher than what was reported by Rajeswari R and his co investigators in which only 17.3% the prescriptions were with poly pharmacy.…”

Section: Discussionmentioning

confidence: 75%

Prescribing pattern of antibiotics in pediatric wards of Bishoftu Hospital, East Ethiopia

Feleke¹,

Yenet²,

Lenjisa³

2013

Int J Basic Clin Pharmacol

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“…For instances, the study done in southwest Ethiopia, Jimma Hospital, has shown that the average number of drugs per encounter was 1.59 [13]. Additionally, in other study conducted in three hospitals in north Ethiopia, the average number of drugs per patient was 0.98 at Gondar Hospital, 1.8 in Bahir Dar Hospital, and 2.2 in Debre Tabor Hospital [19]. A national baseline study done on drug use indicators of humans in Ethiopia in September 2002 showed the average number of drugs prescribed per encounter to be 1.9 [20].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of rational use of veterinary drugs especially antimicrobials and anthelmintics in Bishoftu, Central Ethiopia

et al. 2015

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BackgroundRational use of drugs in veterinary medicine has numerous benefits, such as increasing efficacy, decreasing the potential adverse effects, reducing risk of drug residue and combating development of microorganism’s drug resistance.MethodsA retrospective study with the aim of evaluating the current rational use of veterinary drugs was conducted at college of veterinary medicine and agriculture veterinary teaching hospital and Ada district veterinary clinic, central Ethiopia. One thousand eight hundred and nineteen animal patients’ encounters were randomly selected for the study from prescription papers and prescription registration books retrospectively.ResultsThe average number of drugs prescribed per encounter was 1.23 with maximum of five. The percentage of encounters in which antimicrobials and anthelmintics was prescribed were 54.4 % (1216/2235) and 38.9 % (869/2235), respectively. The percentages of drugs prescribed by generic name and from essential veterinary drug list were 90.1 % (2014/2235) and 99.7 % (2229/2235), respectively. The most commonly prescribed antimicrobials and anthelmintics were oxytetracycline 1016 (45.5 %), penicillin and streptomycin combination 168 (7.5 %), sulfa drugs 23 (1.0 %), and albendazole 732 (32.8 %) and ivermectin 137 (6.1 %). Among the 1819 animal-patient encounters, only 57 % (n = 1037) of the prescriptions were written adequately, 43 % (n = 782) incorrectly prescribed and 1179 cases of the adequately specified prescription were tentatively diagnosed. For 656 (53.9 %) and 233 (26.8 %) inadequately specified cases antimicrobials and anthelmintics were prescribed, respectively. Antibiotics were prescribed irrationally for cases which were tentatively diagnosed as parasitic 21.6 % (n = 262) and viral to prevent secondary bacterial complications 6.0 % (n = 73). Among all patients that were admitted to veterinary clinics, 96.6 % (1757) were treated empirically without getting correct laboratory-supported diagnosis. Chi Square test for trend analysis showed a statistically significant association between irrational drug usage and year (p = 0.000).ConclusionsThe findings had shown problems in generic prescribing, incorrect diagnosis, and non-availability of standard veterinary treatment guideline and drug formulary in the study area. Therefore, veterinary drugs, specially, antimicrobial agents should be judiciously used; and a wide scale study to safeguard the public from drug residual effects and antimicrobial resistance development is recommended.

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Drug prescribing patterns for outpatients in three hospitals in north-west Ethiopia

Cited by 30 publications

References 5 publications

Serioprevalence of <i>Helicobacter pylori</i> Infection in and its Relationship with ABO Blood Groups

Serioprevalence of <i>Helicobacter pylori</i> Infection in and its Relationship with ABO Blood Groups

Prescribing pattern of antibiotics in pediatric wards of Bishoftu Hospital, East Ethiopia

Evaluation of rational use of veterinary drugs especially antimicrobials and anthelmintics in Bishoftu, Central Ethiopia

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