2018
DOI: 10.23939/chcht12.04.473
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Drug Micro-Carriers Based on Polymers and Their Sterilization

Abstract: This paper presents the main aspects regarding the production of biodegradable microspheres, the optimization of parameters in the drug encapsulation process, the techniques available for polymeric systems sterilization and the effects of γ-irradiation on microparticles.

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Cited by 21 publications
(4 citation statements)
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References 316 publications
(367 reference statements)
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“…These particles provide several advantages, including the possibility of tailoring their properties to improve the efficiency of available biomedical applications that rely on them. They can be made from both degradable and non-degradable materials [ 48 ]. Over the last decades, successful developments in the polymers chemistry and processing field have catalyzed the design of microparticles with fine-tune characteristics.…”
Section: Fabrication and Modification Of Polymeric-based Microparticl...mentioning
confidence: 99%
“…These particles provide several advantages, including the possibility of tailoring their properties to improve the efficiency of available biomedical applications that rely on them. They can be made from both degradable and non-degradable materials [ 48 ]. Over the last decades, successful developments in the polymers chemistry and processing field have catalyzed the design of microparticles with fine-tune characteristics.…”
Section: Fabrication and Modification Of Polymeric-based Microparticl...mentioning
confidence: 99%
“…[7][8][9][10] Researchers pay special attention to preparing polyesterbased dispersed delivery systems for therapeutic agents. 11 However, polyesters based on dicarboxylic acids and diols 12 or lactones 13 do not include functional groups or active centers capable of chemisorption of biological substances and drugs, that significantly limits their use. Therefore, the synthesis of functionalized polyesters still remains an urgent problem.…”
Section: Introductionmentioning
confidence: 99%
“…Nowadays, the search for high‐performance, environmentally friendly, and low‐cost materials is constantly advancing. [ 7–114 ] According to Google Scholar, during the last decade (2010–2020), 1310000 articles were published in the area of high‐performance materials. They include high‐performance materials produced with polymers, with 12,5000 articles registered.…”
Section: Introductionmentioning
confidence: 99%