Drosophila viewer: a program on the formal genetics, anatomy and developmental biology of Drosophila melanogaster for students and specialists

Otto, Paulo Alberto

doi:10.1590/s1415-47572000000400022

Cited by 5 publications

(3 citation statements)

References 1 publication

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“…In the first experiment, we placed PS, F1 or BC larvae into competition against the larvae of D. pseudoobscura OR-PX (hereafter OR-PX) and quantified the number of flies that eclosed. OR-PX carries both an eye color ( orange ) and wing vein mutation ( plexus ) allowing it to be distinguished easily from the PS, F1 or BC progeny by the presence of additional cross-veins [ 79 ]. Because OR-PX is a weak competitor (Myers, unpublished data), this experiment established baseline competitive ability of each offspring class while avoiding interactions among focal classes.…”

Section: Methodsmentioning

confidence: 99%

Multifaceted, Cross-Generational Costs of Hybridization in Sibling Drosophila species

et al. 2013

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Maladaptive hybridization, as determined by the pattern and intensity of selection against hybrid individuals, is an important factor contributing to the evolution of prezygotic reproductive isolation. To identify the consequences of hybridization between Drosophila pseudoobscura and D. persimilis, we estimated multiple fitness components for F1 hybrids and backcross progeny and used these to compare the relative fitness of parental species and their hybrids across two generations. We document many sources of intrinsic (developmental) and extrinsic (ecological) selection that dramatically increase the fitness costs of hybridization beyond the well-documented F1 male sterility in this model system. Our results indicate that the cost of hybridization accrues over multiple generations and reinforcement in this system is driven by selection against hybridization above and beyond the cost of hybrid male sterility; we estimate a fitness loss of >95% relative to the parental species across two generations of hybridization. Our findings demonstrate the importance of estimating hybridization costs using multiple fitness measures from multiple generations in an ecologically relevant context; so doing can reveal intense postzygotic selection against hybridization and thus, an enhanced role for reinforcement in the evolution of populations and diversification of species.

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Section: Methodsmentioning

confidence: 99%

Multifaceted, Cross-Generational Costs of Hybridization in Sibling Drosophila species

et al. 2013

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“…This is a short notice announcing the publication of an e-book by the Brazilian Society of Genetics (SBG) and reviewing it. The publication ("Elementary Atlas of Drosophila melanogaster Mutations") is a direct descendent of the computer program "Drosophila Viewer" ( Otto, 2000a , b ) which is still available at the author's internet site https://www.ib.usp.br/~otto/drosoview.html). The program was designed to run on Windows versions 3.1 and 95 and still works on Windows XP, but on modern PC computers with the latest versions of Windows it will run only when loaded into virtual partitions able to contain older versions of Windows.…”

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confidence: 99%

“…Formal permission for all extra material included in the Atlas was obtained directly from the respective corresponding authors and editors listed in the Atlas and in the program "Drosophila Viewer", or in the publications describing it ( Otto 2000 a,b).…”

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confidence: 99%

Elementary Atlas of Drosophila melanogaster Mutations

Otto

2022

Genet. Mol. Biol.

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This is a short notice announcing the publication of an e-book by the Brazilian Society of Genetics (SBG) and reviewing it. The publication ("Elementary Atlas of Drosophila melanogaster Mutations") is a direct descendent of the computer program "Drosophila Viewer" (Otto, 2000a,b) which is still available at the author's internet site https://www.ib.usp. br/~otto/drosoview.html). The program was designed to run on Windows versions 3.1 and 95 and still works on Windows XP, but on modern PC computers with the latest versions of Windows it will run only when loaded into virtual partitions able to contain older versions of Windows.The contents of the e-book, like those of the program "Drosophila Viewer," with a focus on non-specialized audiences, should interest primarily students and professionals specialized in the teaching of Genetics.At approximately the same time the program "Drosophila Viewer" was produced, the internet online resources on Drosophila genetics, anatomy, development and molecular biology grew substantially, especially those from the FlyBase organization (http://flybase.bio.indiana.edu/), sponsored by the University of Indiana at Bloomington, Indiana. The FlyBase site houses an incredible number of files dedicated to the detailed, in-depth biology of Drosophila, including the excellent collection of photographs of classical phenotypic mutants by Holtzman and Kaufman (2013). The (also excellent) "Learning to Fly" poster by Childress et al. (2005) can also be accessed in the internet. The photos from this poster inspired many divulgation works of phenotypic mutations in the fly, such as the cornerstone 2013 book "Atlas of Drosophila Morphology," by Chyb and Gompel, with photographs obtained [just like the images of Holtzman and Kaufman (2013) and Childress et al. (2005)] by using state-of-the-art Leitz's Leica multifocal equipment and a careful setup of living flies with phenotypic mutations.In order to keep alive the graphic material from the "Drosophila Viewer" program and organize everything as an elementary Atlas on phenotypic mutations of Drosophila, the e-book was produced by working on all the original drawings used in the program and adding material obtained with permission from other sources, especially from Professors Thomas C. Kaufman (photos by Holtzman & Kaufman 2013

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Genetic Systems, Genome Evolution, and Genetic Control of Embryonic Development in Insects

Hoy¹

2013

Insect Molecular Genetics

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Drosophila viewer: a program on the formal genetics, anatomy and developmental biology of Drosophila melanogaster for students and specialists

Cited by 5 publications

References 1 publication

Multifaceted, Cross-Generational Costs of Hybridization in Sibling Drosophila species

Multifaceted, Cross-Generational Costs of Hybridization in Sibling Drosophila species

Elementary Atlas of Drosophila melanogaster Mutations

Genetic Systems, Genome Evolution, and Genetic Control of Embryonic Development in Insects

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