Double‐ring sign in granulocyte colony‐stimulating factor‐induced vasculitis

Abstract

Key message If a double‐ring sign is found in contrast‐enhanced computed tomography, this should raise concern not only for Takayasu arteritis, but also for granulocyte colony‐stimulating factor‐induced vasculitis.

Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography revealed the course of granulocyte-colony stimulating factor-associated aortitis: A case report

“…Radiological features are not specific, whereas CT and MRI can reveal the thickened walls [ 2 , 4 ]. Moreover, there was a report of G-CSF-associated aortitis that showed ‘double ring sign’, which is considered specific to TAK [ 10 ]. PET/CT has been used to observe FDG accumulation at thickened walls, and in severe cases, aneurysms, dissections, and ruptures can occur [ 2 , 4 , 8 , [11] , [12] , [13] ].…”