Double-redox cycling signal amplification coupling Mo2C-graphyne-AuNPs modified electrode based photoelectrochemical assay for Aβ1-40 oligomers

Zhang, Jianying; Qin, Nana; Wang, Mingjing; Hun, Xu

doi:10.1016/j.snb.2020.128947

Cited by 8 publications

(2 citation statements)

References 53 publications

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“…In redox-cycling-involved electrochemical bioassays, electroactive species are electrochemically reduced or oxidized and then regenerated by other species. In addition, the photogenerated holes at the photoelectrode can also oxidize electroactive species to trigger redox cycling for signal amplification [ 250 , 251 , 252 ]. Liu’s group developed several photoelectrochemical (PEC) immunosensors by combining redox cycling with enzymatic amplification [ 253 , 254 , 255 ].…”

Section: Hydrolytic Enzymes As Signal Labelsmentioning

confidence: 99%

Overview on the Development of Electrochemical Immunosensors by the Signal Amplification of Enzyme- or Nanozyme-Based Catalysis Plus Redox Cycling

Xia,

Gao,

Zhang

et al. 2024

Molecules

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Enzyme-linked electrochemical immunosensors have attracted considerable attention for the sensitive and selective detection of various targets in clinical diagnosis, food quality control, and environmental analysis. In order to improve the performances of conventional immunoassays, significant efforts have been made to couple enzyme-linked or nanozyme-based catalysis and redox cycling for signal amplification. The current review summarizes the recent advances in the development of enzyme- or nanozyme-based electrochemical immunosensors with redox cycling for signal amplification. The special features of redox cycling reactions and their synergistic functions in signal amplification are discussed. Additionally, the current challenges and future directions of enzyme- or nanozyme-based electrochemical immunosensors with redox cycling are addressed.

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Section: Hydrolytic Enzymes As Signal Labelsmentioning

confidence: 99%

Overview on the Development of Electrochemical Immunosensors by the Signal Amplification of Enzyme- or Nanozyme-Based Catalysis Plus Redox Cycling

Xia,

Gao,

Zhang

et al. 2024

Molecules

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“…Commercially available ascorbic acid (vitamin C) has been used in catalytic and biological chemistry because of its ability to coordinate with metal and reducibility. [ 20,21 ] Glycerol is a benign solvent and features reducibility. [ 22,23 ] As part of our ongoing research on ligand‐promoted copper‐catalyzed CN coupling reactions, [ 24,25 ] we investigated the direct synthesis of various N ‐arylation products in glycerol solvents using CuO and ascorbic acid as the catalyst (Scheme 1).…”

Section: Introductionmentioning

confidence: 99%

Reduction system “vitamin C/glycerol” promoted copper(II)‐catalyzed N‐arylation

Yan

et al. 2022

Applied Organom Chemis

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The common access to forming CN bond is the copper‐catalyzed Ullmann‐type reaction. The relatively expensive and easily oxidized copper(I) is usually used in the reaction. Our group discovered that the “vitamin C/glycerol” reduction system could convert cheap and stable CuO to active low valence state copper species, as measured via X‐ray photoelectron spectroscopy (XPS), to promote the CN coupling reaction. In particular, 2‐phenylindole, pyrrolo[1,2‐a]quinoxaline, 1,2,4‐triazole and 4‐amino‐7H‐pyrrolo[2,3‐d]pyrimidine derivative were obtained in the presence of CuO and reduction system “vitamin C/glycerol.” This method provided a simple and cost‐effective approach to the preparation of N‐arylation products.

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Nanotechnology‐Based Strategies for Early Diagnosis of Central Nervous System Disorders

Hanif

Muhammad

Niu

et al. 2021

Advanced NanoBiomed Research

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Central nervous system (CNS) disorders feature the progressive and selective loss of normal brain functions. CNS disorders often include an irreversible physiological and anatomical loss of neurons that can lead to dysfunction in various parts of the brain and eventually death. Glioblastoma multiforme (GBM) and neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD) are hard to be diagnosed at an early stage for the prevention of disease propagation. Such diagnosis is vital for the timely commencement of actual treatments. Nanotechnology brings new diagnosis hope for CNS disorders as it provides ultrasensitive detection for more specific biomarkers. Herein, the recent progress in techniques development for detecting pathological biomarkers for GBM, AD, and PD is summarized, in particular, the principles that govern the design of these sensors, blood–brain barrier (BBB) dysfunction, and its integrity during disease development. Finally, a perspective on future directions to further advance and improve the early‐stage diagnosis of CNS disorders is presented.

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Double-redox cycling signal amplification coupling Mo2C-graphyne-AuNPs modified electrode based photoelectrochemical assay for Aβ1-40 oligomers

Cited by 8 publications

References 53 publications

Overview on the Development of Electrochemical Immunosensors by the Signal Amplification of Enzyme- or Nanozyme-Based Catalysis Plus Redox Cycling

Overview on the Development of Electrochemical Immunosensors by the Signal Amplification of Enzyme- or Nanozyme-Based Catalysis Plus Redox Cycling

Reduction system “vitamin C/glycerol” promoted copper(II)‐catalyzed N‐arylation

Nanotechnology‐Based Strategies for Early Diagnosis of Central Nervous System Disorders

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