Double-High-Pass-Filter-Based Electrical-Recording Front-Ends and Fluorescence-Recording Front-Ends for Monitoring Multimodal Neural Activity

Lee, Taeju; Je, Minkyu

doi:10.1109/tcsii.2020.2980009

Cited by 8 publications

(8 citation statements)

References 9 publications

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“…All the channels can also be configured in current-recording mode to sense ions and neurotransmitters released by cells. However, if a multimodal neural probe combining electrodes and photodiodes is used to conduct cell-type-specific neural activity monitoring, for example, the voltage-recording and current-recording FEs are both required at the same time [2], [3]. In such a case, the recording IC can reconfigure some FEs in voltage-(or current-) recording mode.…”

Section: Reconfigurable Multimodal Neural Recording Ic a Application Scenariomentioning

confidence: 99%

“…For monitoring Ca 2+ , the photodiode generates a current of pA level by detecting fluorescence due to the interaction between GECIs and Ca 2+ ions [3]. For monitoring neurotransmitters, a current of nA level produced by a chemical reaction occurring at the electrode surface needs to be recorded [5], [9], and [10].…”

Section: B Operation Of the Fcm-rscmentioning

confidence: 99%

“…The FD-AFE amplifies VDiff over the recording BW, which can be adjusted according to the characteristic of the input signal. When monitoring Ca 2+ or neurotransmitters in the current-recording mode, the input signal information resides in a lowfrequency band of several hundred Hz, while the frequency band of APs and LFPs spans from sub-1 Hz to several kHz [3] [5], [9], and [10]. The core circuits from FCM-RSC to SAR ADC operate with a 1-V supply, and the digital I/O is driven by a 1.8-V supply.…”

Section: Overall System Operationmentioning

confidence: 99%

“…For neuroscience study, the modality of voltage recording to detect action potentials (APs) and local field potentials (LFPs) is widely used. In addition to the recording of APs and LFPs, monitoring calcium ions (Ca 2+ ) enables the cell-type-specific study [1] [3], and Ca 2+ can be measured using the genetically encoded calcium indicators (GECIs), which emit the fluorescence when combining with Ca 2+ . The emitted fluorescence is then converted to current by the photodiode.…”

Section: Introductionmentioning

confidence: 99%

“…1 (middle)). Therefore, the voltage-recording FE is used only for voltage-domain signals, while the current-recording FE is used only for current-domain signals [3] [10]. Such an FE dedicated to a specific modality cannot be used to implement a flexible multimodal neural recording system with maximized hardware availability.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

A 5.7µW/Channel Folded-Current-Mirror-Based Reconfigurable Multimodal Neural Recording IC with Improved Hardware Availability

Lee

Kim

Lee

et al. 2021

2021 IEEE International Symposium on Circuits and Systems (ISCAS)

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This paper presents a multimodal neural recording system incorporating reconfigurable neural recording front-ends to improve hardware availability. The proposed neural recording front-end utilizing the reconfigurable signal conveyor based on the folded-currentmirror structure is configured to process either voltage or current input signal, depending on the targeted experiment scenario, given experiment setup, and varying status of the recording environment. Thus, out of the total number of recording channels, how many channels are used for voltage and current recording can be set as desired, which maximizes the flexibility of the experiment and the usefulness of the recording system. The implemented system is successfully applied to the in vivo recording experiment conducted in the hippocampus area of a mouse brain. The neural recording front-end achieves input-referred noise performances of 2.4 μVrms and 5.19 pArms in the voltage and current recording modes, respectively. The power consumed by each recording channel is 5.718 μW, and only 54 nW is used to operate the reconfigurable signal conveyor.

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Section: Reconfigurable Multimodal Neural Recording Ic a Application Scenariomentioning

confidence: 99%

Section: B Operation Of the Fcm-rscmentioning

confidence: 99%

Section: Overall System Operationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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A 5.7µW/Channel Folded-Current-Mirror-Based Reconfigurable Multimodal Neural Recording IC with Improved Hardware Availability

Lee

Kim

Lee

et al. 2021

2021 IEEE International Symposium on Circuits and Systems (ISCAS)

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Research on High Harmonic Amplification of 10kV Series Static Var Generator

Ding

et al. 2023

J. Phys.: Conf. Ser.

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With the continuous development of power electronic devices and science and technology, cables and rectifiers, inverters, DC transmission equipment, and other nonlinear loads have been widely used in power systems. However, this causes harmonic pollution and large capacitive reactive power, which can affect the safe and stable operation of the power system. Based on the analysis of the reasons for the use of static var generator in the power grid and the existing conditions of even harmonic, the impedance analysis method was used to analyze the abnormal noise event of a transformer in a substation. Firstly, the equivalent impedance model diagram is drawn by the equivalent circuit method, and the equivalent impedance value of the system is calculated. A number of harmonic amplifications and the positions of the resonance point are calculated by MATLAB software. Secondly, the correctness of the above theoretical analysis is verified by field test and simulation model built in ETAP software. Finally, because of the abnormal noise of the transformer in a substation caused by harmonic amplification, three harmonic suppression measures are given.

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A High-Precision Single-Ended-Current-to-Differential-Voltage Converter for Reconfigurable Neural Recording Front-Ends

Lee

2021

2021 IEEE International Midwest Symposium on Circuits and Systems (MWSCAS)

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Double-High-Pass-Filter-Based Electrical-Recording Front-Ends and Fluorescence-Recording Front-Ends for Monitoring Multimodal Neural Activity

Cited by 8 publications

References 9 publications

A 5.7µW/Channel Folded-Current-Mirror-Based Reconfigurable Multimodal Neural Recording IC with Improved Hardware Availability

A 5.7µW/Channel Folded-Current-Mirror-Based Reconfigurable Multimodal Neural Recording IC with Improved Hardware Availability

Research on High Harmonic Amplification of 10kV Series Static Var Generator

A High-Precision Single-Ended-Current-to-Differential-Voltage Converter for Reconfigurable Neural Recording Front-Ends

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