Double Filtration Plasmapheresis

Agishi, Tetsuzo; Kaneko, Itaru; Hasuo, Y; Hayasaka, Y; Sanaka, Tsutomu; Ota, Kazuo; Amemiya, H; Sugino, Nobuhiro; M, Abe; Ono, Taketoshi; S, Kawai; Yamane, Takeo

doi:10.1046/j.1526-0968.2000.00237.x

Cited by 53 publications

(57 citation statements)

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“…In advance countries including United States the plasmapheresis involves automated centrifuge. 6 In our study 23 (42.59%) were females, and 31(57.41%) were males. Males to female's ratio was 1.4:1.…”

Section: Discussionsupporting

confidence: 45%

Plasmapheresis; An Experience in Blood Bank of a Tertiary Care Hospital in Peshawar

Qureshi

Khan

2017

TPMJ

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ABSTRACT… Objectives:To determine the frequency of major indications require plasmapheresis in blood bank of Lady Reading Hospital Peshawar. Study Design: Cross sectional study. Setting: Blood bank of Lady Reading Hospital Peshawar. Period: June 2010 to June 2012. Material and methods: Relevant information's were recorded on a pre-designed questionnaire prepared in accordance with the objectives of the study. Results: A total of 54 patients were enrolled in the trial. 23 (42.59%) were females, and 31(57.41%) were males. Males to females ration was 1.4:1. We received patients for plasmaphersis in age ranging from 15 to 74 years. Majority were young patients in age range 15 to 34 years age. We received majority of the patients for the subject procedure from ICU (Intensive care unit) 20(73%), followed by cardiothoracic unit 17(31.48%). We also receive two volunteers during study. The frequency of various indications for plasmapheresis were; myasthenia gravis 29(53.7%), Guillen barre syndrome 20(37.04%) and thrombocytopenic purpura 3(5.56%). Conclusion. From this study we concluded that that autoimmune diseases are common in younger age which is a very serious concern for our society. Plasmapheresis is a therapeutic procedure as well and patients with autoimmune disorders get relieved with it symptomatically as autoimmune antibodies are removed. Myasthenia gravis was counted as major disease followed by GBS and thrombocytopenic purpura in our population. Key words:Autoimmune disorders, Plasmapheresis, Peshawar.

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Section: Discussionsupporting

confidence: 45%

Plasmapheresis; An Experience in Blood Bank of a Tertiary Care Hospital in Peshawar

Qureshi

Khan

2017

TPMJ

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“…We summarize the characteristics of these 8 methods, including their advantages, disadvantages, and their LDL reduction rates in table 2 [5][6][7][8][9][10][11][12] . All of the methods involve non-selective removal of LDL by plasma exchange [5] , semi-selective removal of LDL via pore size using DFPP [6] , and other selective removal of LDL, such as immuno-adsorption [7] , biochemical precipitate [8] , and electrostatic interaction [10][11][12] . In clinical practice, plasma exchange is rarely used due to its lack of selectivity and thermofiltration.…”

Section: Discussionmentioning

confidence: 99%

Long-Term Follow-Up of a Homozygous Familial Hypercholesterolemic Patient Receiving Regular Double Filtration Plasmapheresis - Case Report and Literature Review

Tsai

Wu²,

Shu³

et al. 2016

Blood Purif

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Homozygous familial hypercholesterolemia (HoFH) is a very rare condition (1 case per 1 million people) with a dismal outcome due to inevitable coronary artery disease that occurs when left untreated. Lipoprotein apheresis (LA), previously known as low-density lipoprotein (LDL) apheresis, is very effective in reducing LDL-cholesterol (LDL-C) if HoFH is refractory to aggressive drug therapy and diet control. In this study, we report a case with HoFH, who presented with xanthomata over the 4 limbs when she was 3 years old. When she was 11 years old, she began treatment with semi-selective LA with double filtration plasmapheresis (DFPP) once per week because HoFH was refractory to high-dose statin and diet control. LDL-C was reduced from 8.2 ± 0.9 to 2.69 ± 0.75 mmol/l (reduction rate = 67.3 ± 6.1%). The xanthomata over the 4 limbs were nearly completely resolved after 2 years of DFPP. Two years later, after the initiation of DFPP, we performed coronary angiography and echocardiography for regular checkup in the absence of chest pain, and the result was negative. To date (11 years after initiation of DFPP), she has not complained of any chest pain, shown intolerance to exercise, or exhibited ST-T change on electrocardiography. At the age of 20, multidetector computed tomography showed no significant stenosis over the coronary arteries. At the most recent follow-up visit, she was found to have good heart function and no xanthomata. LA is effective in the treatment of HoFH when drug therapy and diet control fail. With this treatment, pre-existing xanthomata can regress and coronary artery disease can be prevented.

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“…To remove anti-blood group antibodies, all patients underwent three or four sessions of double-filtration plasmapheresis (DFPP) before transplantation according to a previously reported protocol (14). Briefly …”

Section: Desensitizing Protocolmentioning

confidence: 99%

Acute Antibody-Mediated Rejection in Living ABO-Incompatible Kidney Transplantation: Long-Term Impact and Risk Factors

Toki

Ishida

Setoguchi

et al. 2009

American Journal of Transplantation

107

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Double Filtration Plasmapheresis

Cited by 53 publications

References 0 publications

Plasmapheresis; An Experience in Blood Bank of a Tertiary Care Hospital in Peshawar

Plasmapheresis; An Experience in Blood Bank of a Tertiary Care Hospital in Peshawar

Long-Term Follow-Up of a Homozygous Familial Hypercholesterolemic Patient Receiving Regular Double Filtration Plasmapheresis - Case Report and Literature Review

Acute Antibody-Mediated Rejection in Living ABO-Incompatible Kidney Transplantation: Long-Term Impact and Risk Factors

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