Double blind comparative trial of abana and methyldopa for monotherapy of hypertension in Indian patients.

Dadkar, Vaishali N; R, Tahiliani; Jaguste, Veena; Damle, Vasudha; Dhar, Harsh

doi:10.1536/ihj.31.193

Cited by 13 publications

(6 citation statements)

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“…Clinically and statistically significant fall in BP was seen early at 2 weeks in comparison to other herbal formulations studied for their antihypertensive effect. [ 2 7 21 ] Normotensive effect of the drug in terms of SBP and DBP was observed in all the patients. Results were better in Stage II than in Stage I, reflecting its high efficacy in regulating BP.…”

Section: Discussionmentioning

confidence: 95%

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A pilot study to clinically evaluate the role of herbomineral compound " Rakatchap Har" in the management of essential hypertension

Nandha¹,

Singh

Moudgill

et al. 2011

AYU

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The aim of the present study was to investigate the clinical efficacy of a herbomineral medicine Rakatchaphar (Each 500 mg cap contains Sarpgandha 150 mg, Shankhpushpi 75 mg, Jatamansi 75 mg, Jahar Mohra Khatai Pishti 75 mg, Moti Pishti 75 mg, Ras Sindoor 50 mg) in essential hypertension, an observational prospective study was done at Shri Ashutosh Maharaj (SAM) Ayurvedic Treatment and Research Centre, Noormahal. Ninety-eight patients in the age group 28–76 years with essential hypertension without any co-morbid illness were included in the study. Patients were treated with cap Rakatchaphar 500 mg twice a day. Blood pressure (BP) was monitored on subsequent follow-up visits at 2, 4, 6, and 8 weeks. Change in Diastolic BP (DBP), Systolic BP (SBP), and Mean BP (MBP) were analyzed statistically by Student's t test, ANOVA, and Post hoc Bonferroni test. On first visit the mean SBP, DBP, and MBP was 164.16±17.27, 101.88±9.20, and 122.27±10.57 mm Hg, respectively. After 8 weeks of therapy there was a statistically significant fall in SBP (122.98±11.36), DBP (80.90±8.57), and MBP (94.86±9.24) in mmHg (P value <0.0001). Rakatchap Har offers an efficacious and safe combination of natural products available for the treatment of hypertension.

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Section: Discussionmentioning

confidence: 95%

“…[ 4 ] In lieu of the fact that the incidence of hypertension is still rising alarmingly, there is dire need to search for an effective and safe magical remedy because of lack of current therapies to either provide complete cure or treating the patients at the cost of adverse effects. [ 5 – 7 ]…”

Section: Introductionmentioning

confidence: 99%

A pilot study to clinically evaluate the role of herbomineral compound " Rakatchap Har" in the management of essential hypertension

Nandha¹,

Singh

Moudgill

et al. 2011

AYU

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“…The therapy with Abana proved to be highly effective in hypertensive patients [Dadkar et al, 1990]. Administration of Abana for 3 days increased the basal amplitude and reduced the responses of atria to isoprenaline and norepinephrine in rabbits [Pasnani et al, 1988].…”

Section: Medical Drugs Of Mumiementioning

confidence: 97%

Medical drugs from humus matter: Focus on mumie

Schepetkin

Khlebnikov

Kwon

2002

Drug Development Research

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In this review, we focus on the medicinal drugs from humus matter such as peat, sapropel, and mumie. The most clinically available medicines, containing peat and sapropel extracts, are Torfot, Tolpa Peat Preparation (TPP), Peloidodistillate, Humisol, Peloidin, FiBS, and Eplir. Much attention in the review is concentrated on mumie composition, its pharmacological properties, and new pharmacological drugs with mumie (Shilagen, Abana, Cystone, Diabecon 400, EveCare, Geriforte, Lukol, Pilex, Rumalava, Tentex forte, Nefrotec, Adrenotone, Siotone, La-Tone Gold, Andro-Surge, Solanova Libidoplex). It was concluded that therapeutic properties of crude extracts from peat, sapropel, and mumie have similarity to the ones of fulvic and humic acids. They are antibacterial, antitoxic, antiradical, antiulcerogenic, antiarthritic, immunomodulatory, and antiinflammatory properties. Possible directions for better development of new drugs from humus matter are discussed. Drug Dev.

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“…Abana ® has been reported to be beneficial in several cases of hypertension and angina pectoris. In India, it has been clinically used from several decades to treat hyperlipidemia, hypertension, [13][14][15] and other cardiovascular diseases. [16][17][18] The mechanism behind the beneficial effect of Abana ® in cardiovascular diseases has not been scientifically proven, and henceforth this study is useful in exploring those means.…”

Section: Introductionmentioning

confidence: 99%

Anti-platelet and Anti-thrombotic Effects of a Poly-ingredient formulation: In vitro and in vivo experimental evidences

Viswanatha¹,

Rafiq²,

Rajesh³

et al. 2012

Oman Med J

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Double blind comparative trial of abana and methyldopa for monotherapy of hypertension in Indian patients.

Cited by 13 publications

References 1 publication

A pilot study to clinically evaluate the role of herbomineral compound " Rakatchap Har" in the management of essential hypertension

A pilot study to clinically evaluate the role of herbomineral compound " Rakatchap Har" in the management of essential hypertension

Medical drugs from humus matter: Focus on mumie

Anti-platelet and Anti-thrombotic Effects of a Poly-ingredient formulation: In vitro and in vivo experimental evidences

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