Dose-dependent induction of heat shock protein 70 synthesis in Raphidocelis subcapitata following exposure to different classes of environmental pollutants

Characterization of the small heat shock protein Hsp27 gene in Chironomus riparius (Diptera) and its expression profile in response to temperature changes and xenobiotic exposures

“…HSPs were first discovered under heat shock and were later found to be highly abundant in cells submitted to many other chemical and physical stimuli in a wide range of species. In general, Hsp genes are expressed at low levels under normal growing conditions, but their expression increases considerably in a rapid response to different forms of stressors including heat, hypoxia, chemical exposures, infections, magnetic fields, and tumorigenesis (Parsell and Lindquist 1993;Feder and Hofmann 1999;Bierkens et al 1998). In arthropods, they are induced by environmental stressors such as heat, desiccation, and heavy metals (Hoffmann and Parsons 1991;Tammariello et al 1999;Hoffmann et al 2003).…”

Expression of heat shock protein 70 in a permanent cell line (EPC) exposed to sediment extracts from the North Sea and the Baltic Sea

“…Increasing occurrence of damaged proteins due to xenobiotics or other forms of stress leads to elevated stress protein content. Numerous inorganic and organic xenobiotics are well known for their ability to induce the synthesis of hsp70 (Salminen et al, 1996;Bierkens et al, 1998;Schröder et al, 1999;Kilemade & Mothersill, 2001). …”

Activation of a stress‐induced gene by insecticides in the midge, Chironomus yoshimatsui

“…However, data on the specificity of HSP70 induction and the dose-response relationship between pollution and stress protein synthesis, especially in aquatic organisms, are limited [8]. As one of such trials, Bierkens et al [9] have shown the possibility that in green alga, HSP70 gene is a sensitive biomarker for different classes of environmental pollutants.…”