Donovanose

Abstract

Abstract:The authors present images of two of the most common clinical forms of granuloma inguinale (donovanosis) in males and females. Donovanosis is considered a sexually transmitted disease that is endemic in tropical and subtropical regions of the world. Two microscopic images are also shown, one of a direct smear (the presence of Donovan bodies within large mononuclear cells identified using Giemsa stain) and the other of typical histological findings (rod-shaped Donovan bodies within a mononuclear histiocyte). Keywords: Communicable diseases; Genital diseases, female; Genital diseases, male; Sexually transmitted diseases; Sexually transmitted diseases, bacterial Resumo: Os autores apresentam imagens de duas formas clínicas mais frequentes da Donovanose, em ambos sexos. A donovanose é considerada uma doença sexualmente transmissível, endêmica nas regiões tropicais e semitropicais do globo. Apresentam também imagens de duas lâminas: uma da pesquisa direta (corpúsculos de Donovan, dentro de grandes células mononucleadas coradas de vermelho pelo Giemsa) e outra de achados histológicos típicos (formato de alfinete dentro do histiócito). Palavras-chave: Doenças bacterianas sexualmente transmissíveis; Doenças dos genitais femininos; Doenças dos genitais masculinos; Doenças sexualmente transmissíveis; Doenças transmissíveis

Donovanosis

“…From a practical standpoint, it is not possible to rule out the diagnosis of donovanosis in a patient with this diagnostic hypothesis considering only the absence of the disease in their sexual partners in the last six months. 28 , 29 …”

Donovanosis in a child victim of sexual abuse: response to doxycycline treatment

“…Diagnosis is based on the clinical characteristics of the lesions and on the identification of the bacteria 5 . K. granulomatis is an intracellular organism that, when phagocyted by large histiocytes, forms DC.…”