Donor Quality of Life up to Two Years After Living Donor Liver Transplantation

Kroencke, Sylvia; Nashan, Björn; Fischer, Lutz; Erim, Yeşim; Schulz, Karl‐Heinz

doi:10.1097/01.tp.0000438206.04348.b2

Cited by 44 publications

(39 citation statements)

References 24 publications

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“…13,14,[33][34][35][36][37][38][39][40][41] The SF-36 is the most frequently used tool for measurement of HRQoL, and the scores are comparable to the findings in our present study. [34][35][36][37]40,41 Compared with the HRQoL shown in the general population, liver donors had equal scores in most examinations. 35,37,41 However, some studies found decreased physical and psychologic scores postoperatively.…”

Section: Discussionsupporting

confidence: 80%

“…[34][35][36][37]40,41 Compared with the HRQoL shown in the general population, liver donors had equal scores in most examinations. 35,37,41 However, some studies found decreased physical and psychologic scores postoperatively. 33 The physical aspects of HRQoL appear to be especially decreased in the early postoperative period.…”

Section: Discussionmentioning

confidence: 99%

“…33 The physical aspects of HRQoL appear to be especially decreased in the early postoperative period. 13,36,37 Further risk factors for an impairment of the donors' HRQoL are the death of the recipient 34 and predonation concerns and time to donation > 4 weeks. 35 Regarding the influence of postoperative complications on HRQoL, there are controversial findings.…”

Section: Discussionmentioning

confidence: 99%

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Untitled

Benzing

Schmelzle²,

Öllinger³

et al. 2018

Exp Clin Transplant

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Section: Discussionsupporting

confidence: 80%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Untitled

Benzing

Schmelzle²,

Öllinger³

et al. 2018

Exp Clin Transplant

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“…In addition, the elevated rates of these problems are reported in the same literature—and sometimes within the same study—that also reports that liver donors’ generic HRQOL meets or exceeds that of the general population. 6,12,20,27,28 This suggests that generic measures may be insensitive for living donors and should be used primarily as adjuncts to more sensitive, specific assessment of donors’ potential problems. 6,12,29,30 …”

Section: Introductionmentioning

confidence: 99%

Psychosocial Outcomes 3 to 10 Years After Donation in the Adult to Adult Living Donor Liver Transplantation Cohort Study

et al. 2016

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Background Studies of liver donors’ psychosocial outcomes focus on the short-term and rely largely on quality-of-life measures not specific to donation. We sought to examine long-term donation effects on three psychosocial domains: perceived physical, emotional, and socioeconomic outcomes. Methods Individuals donating 3–10 years previously at nine centers were eligible for telephone surveys. Survey responses were examined descriptively. Cluster analysis was used to identify distinct donor groups based on response profiles across psychosocial domains. Potential predictors of response profiles were evaluated with regression analysis. Results 517 donors (66%) participated (M=5.8 years postdonation, SD=1.9). 15%–48% of donors endorsed current donation-related physical health problems and concerns, and 7%–60% reported socioeconomic concerns (e.g., insurance difficulties, financial expenditures). However, on average, donors experienced high psychological growth, and 90% felt positively about donation. Cluster analysis revealed five donor groups. One group showed high psychological benefit, with little endorsement of physical or socioeconomic concerns (15% of donors). Four groups showed less favorable profiles, with varying combinations of difficulties. The largest such group showed high endorsement of physical concerns and financial expenditures, and only modest psychological benefit (31% of donors). Men and non-Hispanic whites were most likely to have unfavorable response profiles (p<.01). Compared with donors aged 19–30, older donors were less likely to have unfavorable profiles; these differences were significant for donors aged >40–50 (p’s<.008). Conclusions Even many years postdonation, donors report adverse physical and socioeconomic effects, but positive emotional effects as well. Identification of response profiles and predictors may improve targeting of postdonation surveillance and care.

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“…Therefore, expanding the donor pool and reducing waiting list mortality is one of the major challenges today for the liver transplant community. 4 Increasing the frequency of living donor liver transplantations (LDLT) meets both of those challenges 5,6 This article collates online resources related to LDLT with relevance to the readership of Transplantation.…”

mentioning

confidence: 99%