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Benzing, Christian; Schmelzle, Moritz; Öllinger, Robert; Gruettner, Katharina; Muehlisch, Anja-Kathrin; Raschzok, Nathanael; Sauer, Igor M.; Bahra, Marcus; Pratschke, Johann; Guel-Klein, Safak

doi:10.6002/ect.2017.0108

Cited by 9 publications

(7 citation statements)

References 38 publications

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“…In the published literature, post-donation morbidity rates among liver donors vary from 15 to 78.3% (1,11,19,25,(31)(32)(33)(34)(35)(36)(37)(38)). These complication rates, which vary significantly, were due to the different parts of the liver donated by the included donors.…”

Section: Discussionmentioning

confidence: 99%

“…However, when further analyses of each subscale of SF-36 were performed, different findings were revealed. Benzing et al (11) found a significantly higher score only in the general health perception domain of SF-36. Dew et al (12) found that the mentally related quality of life score was poorer than the normative mean.…”

Section: Introductionmentioning

confidence: 96%

“…Some studies compared the HRQoL of living liver donors with the general population by reporting the score of each subscale of the Medical Outcomes Study Short Form-36 . Studies from Iran (8), Japan (9), Canada (10), and Germany (11) indicated that the overall HRQoL of living liver donors was significantly better than that of the matched sample from the general population of their own countries. However, when further analyses of each subscale of SF-36 were performed, different findings were revealed.…”

Section: Introductionmentioning

confidence: 99%

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Health-Related Quality of Life in Predominantly Young Parental Living Liver Donors: A Cross-Sectional Study in China

et al. 2021

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Objective: The health-related quality of life (HRQoL) of donors deserves attention and must be considered for a long time. Many of the published studies had small sample sizes, and research from mainland China, in particular, is scant. Thus, this study aimed to investigate the HRQoL of living liver donors and identify the influencing factors of the HRQoL in mainland China.Methods: This is a cross-sectional study. The data were collected from the liver transplantation center, the Tianjin First Center Hospital, China. Living liver donors older than 18 years and at a minimum of 1-month, post-donation was included. The HRQoL was evaluated using the Medical Outcome Study Short form 36 (SF-36). Sociodemographic and clinical-related variables, HRQoL status, and its potential impact factors were analyzed.Results: A total of 382 living liver donors completed the survey. The median number of months post-donation was 25, and parental donors (99.2%) were the most frequent relationship. The majority of the participants (372, 97.4%) donated their left lateral lobes. Thirty-two (8.4%) donors suffered complications, and of them, 7 suffered from biliary leakage (1.8%), which was the most common one in this study. The physical functioning (PF), role–physical (RP), bodily pain (BP), general health (GH), social functioning (SF), role–emotional (RE), and mental health (MH) scores among the living liver donors were significantly better than those of the Chinese norms. Short-time post-donation [odds ratio (OR): 0.008; p < 0.001] and male recipients (OR:0.195; p = 0.024) were associated with the likelihood of a poor physical related quality of life.Conclusions: Despite, in general, good HRQoL outcomes, we also believed that liver donation has an obvious influence on the physical functions of liver donors. More attention and long-term follow-ups are necessary for donors at higher risk based on identified influencing factors and correlates.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

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Health-Related Quality of Life in Predominantly Young Parental Living Liver Donors: A Cross-Sectional Study in China

et al. 2021

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“…Many multi-centre cohort studies and longitudinal studies have been done to illustrate the influence of donation on QoL of donors in medical complications, emotional distress, social support and mental well-being (Benzing et al, 2018;Butt et al, 2018;Janik et al, 2019). For example, the Adult-to-Adult Living Donor Liver Transplantation Cohort Study (A2ALL) reported that liver donation could affect donors' physical and socioeconomic status (Nydam et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Living well or not? Quality of life of parental living liver donors: A cross‐sectional study

Chen

Fan

et al. 2023

Journal of Clinical Nursing

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Aim:The aim of this study was to gain comprehensive insight into the quality of life of parental living liver donors after liver donation.Background: Several studies reported good quality of life of living liver donors with the SF-36 scale. Care demand from the recipient and responsibility of being parent might make a difference in parental donors' personal experienced quality of life after transplantation surgery. Methods: It is a cross-sectional study. The parental donors' demographics, clinical data and post-donation complications were obtained. Quality of life was assessed using the Medical Outcomes Study SF-36 and the Quality of Life Scale of Living Organ Donors-Common Module. Patient or Public Contribution:The enrolled participants were contacted by electronic questionnaires and telephonic interview.Results: A total of 345 parental donors were included, with recruited period ranging from 3 to 85 months post-donation. 8.1% of donors had post-operative complications, mostly classified as Clavien grade II. Donors' general quality of life was higher than the Chinese general norm. Issues related to surgical incision, fatigue, worries about income and personal health, effects on work capability, increased medical expenses and difficult reimbursement and suspected donation decision were the prominent problems among donors. Mother-son relationship (OR = 1.87) and equal or less than 2 years after donation (OR = 3.08) were the influencing factors for poor physical quality of life, while unmarried status (e.g. divorced or widowed) was found negatively associated with mental quality of life (adjusted OR = 3.61).Conclusions: General health among parental donors is good but those female, unmarried and near post-donation might in low life quality. Incision, fatigue, finance, reimbursement and donation decision are prominent problems.Relevance to Clinical Practice: Post-donation care of living donors should cover social and financial domain besides physical and mental dimension. Providing follow-up care and counselling is necessary to ensure their life quality.

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“…Moreover, the donations made by LLDs may affect their later daily lives. Although the levels of health-related quality of life in LLDs are not different or even higher than those in the general population [5][6][7][8], donation could be a factor that affects later health-related quality of life (HRQOL). Hesimov et al [9] revealed that the physical aspects of the quality of life in LLDs decreased immediately after surgery and recovered over the first year.…”

Section: Introductionmentioning

confidence: 99%

Does living liver donors’ underestimation about surgical outcomes impact on their health-related quality of life after donation?: a descriptive cross-sectional study

Lee

Koh

et al. 2022

Health Qual Life Outcomes

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Background In South Korea, the number of living-donor liver transplantations in 2019 was 1,188. Living liver donors (LLDs) undergo surgery and the postoperative recovery process for altruistic purposes. This study explored LLDs’ unmet expectations about surgical outcomes and examined their impact on the donors’ health-related quality of life (HRQOL). Methods This descriptive cross-sectional study utilized a self-reported survey. Data were collected at a university hospital in Seoul, South Korea. Among the 535 LLDs who underwent surgery for donation between January 2011 and March 2021, 124 participated in this study. The Korean version of the 12-item Short Form Health Survey version 2 (SF-12v2) was used to measure the HRQOL of LLDs. Unmet expectations regarding surgical outcomes were measured using four items: pain, length of hospital stay, speed of recovery, and complications. Logistic regression model was applied to determine whether the unmet expectations influence HRQOL in LLDs. Odds ratios with 95% confidence interval were used. Results The percentage of the participants who reported that their actual experiences for pain, speed of recovery, hospital stay, and complications were worse than expected were 34.7%, 22.6%, 9.7%, and 7.3%, respectively. Unmet expectations about surgical outcomes were significantly associated with physical and mental HRQOL after controlling for age, sex, education level, income, postoperative complications, recipients’ death, time since donation, and satisfaction with the decision to donate. Conclusion LLDs should be supported in obtaining more accurate and realistic information about surgical outcomes to decrease unmet expectations, which may help improve their quality of life.

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Cited by 9 publications

References 38 publications

Health-Related Quality of Life in Predominantly Young Parental Living Liver Donors: A Cross-Sectional Study in China

Health-Related Quality of Life in Predominantly Young Parental Living Liver Donors: A Cross-Sectional Study in China

Living well or not? Quality of life of parental living liver donors: A cross‐sectional study

Does living liver donors’ underestimation about surgical outcomes impact on their health-related quality of life after donation?: a descriptive cross-sectional study

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