Donation after cardiac death: results of the SUMMA 112 – Hospital 12 de Octubre Program

Abstract

DACD is an adequate source of organs for kidney transplantation. Our functional and survival results are encouraged in the short term, although further work is required to increase the program's benefits.

Kidney transplantation from donors after uncontrolled circulatory death: the Spanish experience

“…Several centers have published the outcomes of kidneys from uDCD donors. 5,6,[10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25] However, to our knowledge, the present study is the most extensive one yet to describe the results obtained with uDCD donor kidneys based on data obtained from a national registry. The study allows us to describe current practices in uDCD and identify factors with an impact on posttransplant outcomes-findings that can help in designing better local protocols and in making decisions about organ allocation.…”

“…2 Individual centers have reported successful outcomes of kidneys transplanted from uDCD donors. 5,6,[10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25] Adequate short-and mid-term graft survival has been observed, albeit with an increased incidence of primary nonfunction (PNF) and delayed graft function (DGF) compared with recipients of kidneys donated after brain death. However, large multicenter studies have not been published to help understand the factors related to the donor, donation procedure, and recipient that have a potential impact on posttransplant outcomes.…”

Uncontrolled donation after circulatory death: European practices and recommendations for the development and optimization of an effective programme

“…uDCD relates to excellent long-term kidney graft survival, despite an increased incidence of primary nonfunction (PNF) and delayed graft function (DGF) [9][10][11][12][13][14][15][16][17][18][19][20][21]. The results of liver transplantation from uDCD donors are mixed and do not consistently provide similar outcomes compared with livers from donation after brain death (DBD) donors, mainly because of a higher incidence of primary graft dysfunction, graft nonfunction and biliary complications [22][23][24][25][26][27].…”

“…C [3,[9][10][11][12][13][14][15][16][17][18][19][20][21] (kidney) [23][24][25][26][27][57][58][59][60] (liver)…”

Establishment of a Novel in Vivo Rabbit Model for Hypothermic Machine Perfusion

“…Organ transplantation has become the effective treatment for end-stage renal disease [1].Since DCD was approved by WHO [2], DCD has become an increasingly used source internationally for the past decade [3][4][5]. Nevertheless, compared to DBD donor, DCD has some shortcomings [3].…”