Domperidone for lactating women

Silva, Orlando P. da; Knoppert, David

doi:10.1503/cmaj.1041054

Cited by 18 publications

(14 citation statements)

References 7 publications

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“…Academic publications presented many cases of induced lactation experiments using galactagogues, a class of medications that initiate and/or increase milk production (8,(49)(50)(51)(52)(53)(54)(55)(56). In addition, there have been several studies conducted on induced lactation practices, such as examining the success of induced lactation in non-pregnant women (17); identifying the processes that promote milk production for women who want to induce lactation (8); exploring motivating factors or reasons for why women want to breastfeed their adopted children (5,48) and gathering experiences of induced lactation (57,58).…”

Section: Breastfeeding Adopted Children: An Islamic Perspectivementioning

confidence: 99%

The Availability of Information on Induced Lactation in Malaysia

Rahim

Sulaiman

Ismail

2017

MJMS

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Induced lactation is a method of stimulating the production of breast milk in women who have not gone through the process of pregnancy. Recent advances in technology have given such women the opportunity to breastfeed adopted children. Previous studies conducted in Western countries have explored the breastfeeding of adopted children, as well as the experiences, successes and challenges of this process. However, research on procedures for breastfeeding adopted children is lacking in Malaysia. The authors have therefore reviewed literature related to induced lactation in Malaysia to fill this gap. Of the 30 related articles identified, 19 described the breastfeeding practices and experiences of adoptive mothers in Malaysia. Out of 19 articles, there were four journal articles, five circulars and regulations, two books, two post-graduate theses, four blogs posts and forum discussions, and two online newspaper articles. Medical information relating to induced lactation procedures was also reviewed, showing that there was a lack of scientific studies focusing on induced lactation practices among adoptive mothers. Information on religious, specifically Islamic, perspectives on breastfeeding and child adoption laws was gathered from websites, social networks, blogs, magazines and online news sources. In consideration of recent advancements in medical technology and the dire need among Malaysians, it is crucial that evidence-based, accurate and reliable information on induced lactation is made available to professionals and other individuals in this country.

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Section: Breastfeeding Adopted Children: An Islamic Perspectivementioning

confidence: 99%

The Availability of Information on Induced Lactation in Malaysia

Rahim

Sulaiman

Ismail

2017

MJMS

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“…Mothers with cardiac diseases should avoid using this drug due to potential arrythmia (43). Domperidone is less permeable through the blood/brain barrier than metoclopramide as it is less soluble, has a higher molecular weight and binds to plasma proteins more strongly (31,39,41,44).…”

Section: Side Effects For Mother and For Infantmentioning

confidence: 99%

“…However, additional investigations are necessary to determine the minimum effective dose and the needed duration of therapy (43).…”

Section: Side Effects For Mother and For Infantmentioning

confidence: 99%

Safety and Efficacy of Galactogogues: Substances that Induce, Maintain and Increase Breast Milk Production

Zuppa¹,

Sindico²,

Orchi³

et al. 2010

J Pharm Pharm Sci

165

168

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Poor production of breast milk is the most frequent cause of breast lactation failure. Often, physician prescribe medications or other substances to solve this problem. The use of galactogogues should be limited to those situations in which reduced milk production from treatable causes has been excluded. One of the most frequent indication for the use of galactogogues is the diminution of milk production in mothers using indirect lactation, particularly in the case of preterm birth. The objective of this review is to analyze to the literature relating to the principal drugs used as galactogogues (metoclopramide, domperidone, chlorpromazine, sulpiride, oxytocin, growth hormone, thyrotrophin releasing hormone, medroxyprogesterone). Have been also analyzed galactogogues based on herbs and other natural substances (fenugreek, galega and milk thistle). We have evaluated their mechanism of action, transfer to maternal milk, effectiveness and potential side effects for mother and infant, suggested doses for galactogogic effect, and recommendation for breastfeeding.

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“…5,6 Domperidone is a peripherally acting dopamine antagonist that has an official use as a prokinetic agent. 11 Despite its widespread use as a galactagogue, until recently only a small number of investigators have studied domperidone for this indication. Domperidone is widely used around the world (Canada, Europe, and Australia) as a galactagogue.…”

Section: Journal Of Human Lactation Xx(x)mentioning

confidence: 99%