What is already known on this subject- Omitted medication doses can lead to increased morbidity and mortality. Pharmacy assistants are unregistered members of the pharmacy workforce. There is some evidence that pharmacy assistants can reduce dose omissions when deployed to hospital wards. What this study adds- A model for pharmacy assistants to be deployed into patient-facing roles in secondary care as 'medicines assistants' Preliminary evidence that pharmacy assistants can save nursing time safely by supporting medicines administration. Further evidence that pharmacy assistants can reduce omitted doses.