2001
DOI: 10.1002/1521-4184(200110)334:10<309::aid-ardp309>3.0.co;2-8
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Does [meso-1,2-bis(2,6-dichloro-4-hydroxy-phenyl) ethylenediamine]dichloroplatinum(II) act as an immune response modifier? IV. Inhibition of the proliferation-increasing effect of progressively growing MXT-M-3,2 breast cancer on phagocytes by the title compound

Abstract: In female B6D2F1 mice bearing an MXT‐M‐3,2 breast cancer graft the level of the phagocytic cells (e.g. of granulocytes and macrophages in the spleen and of granulocytes and monocytes in the blood) is significantly elevated. The positive correlation between the number of the phagocytic cells and the weight of the tumor indicates that the MXT‐M‐3,2 breast cancer promotes myelopoiesis, presumably by secretion of hematopoietic growth factors like GM‐CSF. This process can be described for each phagocyte type by a r… Show more

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Cited by 4 publications
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