Does Hyperbaric Oxygen Therapy Work in Facilitating Acute Wound Healing

Dauwe, Phillip; Pulikkottil, Benson J.; Lavery, Lawrence A.; Stuzin, James M.; Rohrich, Rod J.

doi:10.1097/01.prs.0000436849.79161.a4

Cited by 67 publications

(47 citation statements)

References 28 publications

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“…In the case of acute wounds, results of studies show that, when combined with the principles that recommend conventional wound care, HBOT can help the healing process, however, the few controlled studies for this type of wound have at most introduced one level of evidence and "A-II" recommendation, or "reasonable", for the use of HBOT in crush injuries, acute traumatic ischaemia, and compartment syndrome (3,16) .…”

Section: Discussionmentioning

confidence: 99%

“…This pressure increases arterial and tissue oxygen tension (2000 mmHg and 400 mmHg, respectively), which causes most of the physiological and therapeutic effects of this treatment. This therapeutic procedure has a range of positive effects for the healing process, and is consequently prescribed with other treatment in various clinical situations (3) .…”

Section: Introductionmentioning

confidence: 99%

“…HBOT is also indicated to eradicate soft tissue and bone infections that are otherwise difficult to treat by mechanisms that include the destruction of microorganisms, thus improving the function of leukocytes and macrophages (3,6) .…”

Section: Introductionmentioning

confidence: 99%

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Oxigenoterapia hiperbárica para tratamento de feridas

Andrade

Santos

2016

Rev. Gaúcha Enferm.

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Objective:To describe the most common types of wounds indicated for hyperbaric oxygen therapy and the results. Method: Cross-sectional study at a Hyperbaric Centre in the city of Salvador, Bahia, Brazil. The medical records of 200 patients treated with hyperbaric oxygen were reviewed from January to November 2013. The variables of the persons, clinical, indications, number of sessions and wound care were analysed by means of descriptive statistics and the chi-square test of association incorporating Yates's correction with a level of 5%. Results: The wounds that were most frequently indicated for hyperbaric oxygen therapy were venous ulcers, traumatic injury and diabetic foot. Patients with chronic wounds had fewer sessions (61.1%) and their wounds healed or were reduced (62.0%) compared to those with acute wounds. Conclusion: Hyperbaric oxygen therapy is an eff ective treatment for patients with chronic wounds. Keywords: Wound healing. Hyperbaric oxygenation. Nursing care. RESUMO Objetivo:Descrever os tipos mais frequentes de feridas com indicação para terapia por oxigênio hiperbárico e os resultados obtidos. Método: Estudo transversal, realizado em um Centro Hiperbárico localizado na cidade de Salvador, Bahia. Os prontuários de 200 pacientes tratados com oxigênio hiperbárico foram revisados, no período de janeiro a novembro de 2013, analisando-se as variáveis da pessoa, clínicas, indicação, número de sessões e cicatrização da ferida, através de estatística descritiva e teste de associação Qui--quadrado de Pearson com correção de Yates, adotando-se um nível de 5%. Resultados: As feridas mais frequentemente encontradas como indicação para terapia por oxigênio hiperbárico foram: úlcera venosa, lesão traumática e pé diabético. Os pacientes com feridas crônicas realizaram um menor número de sessões (61,1%) e tiveram suas feridas cicatrizadas ou reduzidas (62,0%) quando comparados com aqueles com feridas agudas. Conclusão: A terapia por oxigênio hiperbárico é um tratamento efetivo para pacientes com feridas crônicas. Palavras-chave: Cicatrização. Oxigenação hiperbárica. Cuidados de enfermagem. RESUMEN Objetivo:Describir los tipos más comunes de heridas con indicación de oxigenoterapia hiperbárica y resultados. Método: Estudio transversal realizado en un centro hiperbárico situado en la ciudad de Salvador, Bahia. Las historias clínicas de 200 pacientes tratados con oxígeno hiperbárico fueron revisados en el período de enero a noviembre de 2013, analizando las variables de la persona, clínicas, la indicación, número de sesiones y la cicatrización de heridas a través de la estadística descriptiva y prueba de chi-cuadrado de asociación con la corrección de Yates, adoptando un nivel de 5%. Resultados: Las heridas que más a menudo se encuentran como una indicación de oxigenoterapia hiperbárica fueron: úlceras venosas, lesiones traumáticas y pie diabético. Los pacientes con heridas crónicas realizaron un menor número de sesiones (61,1%) y tenían sus heridas curándose o reducidas (62,0%) en comparación con aquellos...

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Oxigenoterapia hiperbárica para tratamento de feridas

Andrade

Santos

2016

Rev. Gaúcha Enferm.

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“…It should be emphasised that hyperbaric oxygen therapy (except for poisonings and gas embolism) is supportive and not alternative to surgical treatment or antibiotic therapy, particularly in cases of difficult wound healing and infected acute wounds [5]. Thanks to its direct inhibition of the growth of anaerobic bacteria and stimulation of bactericidal properties of leukocytes fighting aerobic bacteria, hyperbaric oxygen therapy is an essential element supporting the treatment of infections.…”

mentioning

confidence: 99%

“…[5] However, dark episodes in the development of hyperbaric therapy, oxygen therapy in particular, have to be mentioned. Hyperbaric oxygen is an excellent oxidant; therefore, the risk of fire in its atmosphere increases.…”

mentioning

confidence: 99%

Hyperbary – the common roots of treatment of people and exploration of sea depths

Siermontowski¹,

Zieliński²,

Olszański³

2016

APGR

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Elevated ambient pressure is inseparable from exploration of sea depths.The first attempts to design underwater devices almost immediately followed the construction of vehicles to navigate the sea surface. However, it took decades to design a land-based model of hyperbaric conditions and apply them for the treatment of various diseases. Nowadays, hyperbaric therapy is a recognized therapeutic method, which enables the treatment of diving and other underwater accidents. Thanks to long-standing technological advances, medicine and exploration of sea depths have met.

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Compare the effectiveness of extracorporeal shockwave and hyperbaric oxygen therapy on enhancing wound healing in a streptozotocin‐induced diabetic rodent model

Chen,

Lin,

Liu

et al. 2023

The Kaohsiung J of Med Scie

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Studies have revealed that both extracorporeal shock‐wave therapy (ESWT) and hyperbaric oxygen therapy (HBOT) can accelerate wound healing. This study aimed to compare the effectiveness of ESWT and HBOT in enhancing diabetic wound healing. A dorsal skin defect in a streptozotocin‐induced diabetes rodent model was used. Postoperative wound healing was assessed once every 3 days. Histologic examination was performed with hematoxylin and eosin staining. Proliferation marker protein Ki‐67 (Ki‐67), endothelial nitric oxide synthase (eNOS), vascular endothelial growth factor (VEGF), and 8‐hydroxy‐2‐deoxyguanosine (8‐OHdG) were evaluated with immunohistochemical (IHC) staining. The wound area was significantly reduced in the ESWT and HBOT groups compared to that in the diabetic controls. However, the wound healing time was significantly increased in the HBOT group compared to the ESWT group. Histological findings showed a statistical increase in neovascularization and suppression of the inflammatory response by both HBOT and ESWT compared to the controls. IHC staining revealed a significant increase in Ki‐67, VEGF, and eNOS but suppressed 8‐OHdG expression in the ESWT group compared to the HBOT group. ESWT facilitated diabetic wound healing more effectively than HBOT by suppressing the inflammatory response and enhancing cellular proliferation and neovascularization and tissue regeneration.

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Does Hyperbaric Oxygen Therapy Work in Facilitating Acute Wound Healing

Abstract: Therapeutic, II.

Cited by 67 publications

References 28 publications

Oxigenoterapia hiperbárica para tratamento de feridas

Oxigenoterapia hiperbárica para tratamento de feridas

Hyperbary – the common roots of treatment of people and exploration of sea depths

Compare the effectiveness of extracorporeal shockwave and hyperbaric oxygen therapy on enhancing wound healing in a streptozotocin‐induced diabetic rodent model

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