Does ethnic origin have an independent impact on hypertension and diabetic complications?

Abstract

Hypertension and diabetic complication rates were different amongst ethnic subgroups. On logistic regression, it was found that the difference in distribution of age and diabetes duration largely accounted for this difference, although ethnic origin remained an independent risk factor.

Does using ethnic specific criteria improve the usefulness of the term metabolic syndrome? controversies and suggestions

“…Ma et al 77 Similarly, in a cohort of White Caucasian, South Asian and Afro-Caribbean diabetic patients, ethnic origin was found to be an independent risk factor for microvascular and macrovascular complications. 80 More accurate standards are needed to weight the risk for elevated blood glucose levels for T2DM and CVD in different ethnic populations and alter the cutoffs accordingly, as has been done for white Caucasian populations. For example, Lorenzo et al 81 noted that lowering the fasting blood glucose cutoff for the ATP criteria resulted in a better prediction of T2DM in a North American Caucasian population.…”

Disparities in diabetes mellitus among Caribbean populations: a scoping review

“…Furthermore, there was a lack of valid data on other types of physical activity and socioeconomic position measures.Male: 1474Female: 1912Type 2 DMBabwah, 2006 [17]Cross-sectional study360Trinidad and TobagoTrinidad and TobagoUrban clinicReporting bias, lack of multivariate analysis to adjust for known confounders (SES)Male: 93Female: 267Age >13 yearsType 2 DMBarcelo, 2006 [18]Cross-sectional study10,587Barbados vs. MexicoCaribbean, Latin AmericaPopulation-basedNo limitation stated. Prevalence adjusted for known confounders.Male: 4041Female: 6546DM unspecifiedBaskar, 2006 [19]Cross-sectional study6,047Afro-Caribbean vs. Caucasian vs. Indo-AsianUnited KingdomCommunity basedNo limitation stated. Analysis adjusted for known confoundersMale: 3359Female 2688Type 1 & 2 DMCappuccio, 1997 [20]Cross-sectional study1,578Afro-Caribbean vs. West African vs. UK Whites vs. AsiansUnited kingdomCommunity based, general practiceSelection bias in Caribbean group and low response rate.…”

“…Twelve studies investigated disparities in micro-vascular and macro-vascular complications among persons with diabetes [13,14,19,24,27,33,34,37,39,40,45,46,48]. The micro-vascular complications included retinopathy, nephropathy as well as peripheral sensory neuropathy or was not individually specified in the papers reviewed.…”

“…Afro-Caribbeans had a higher prevalence of micro-vascular complications related to diabetes when compared to South Asians and Caucasians in the United Kingdom [19,27,37]. In one study it results were mixed depending on the method of testing for the peripheral sensory neuropathy [13] and in another study that compared Afro-Caribbeans to Caucasians the neuropathy was lower (23 ± 4 vs. 35 ± 3 p = 0.03) though nephropathy (14 ± 3 vs. 11 ± 2 p = 0.6 ) and retinopathy (24 ± 4 vs. 20 ± 3 p = 0.4 ) were higher respectively [39].…”

<i>CAPN10</i> SNP43 G&gt;A gene polymorphism and type 2 diabetes mellitus in the Asian population: a meta-analysis of 9353 participants

“…The significance was not observed in the non-Chinese population, but in the Chinese population, which was probably associated with the different ethnicities in the Asians. Additionally, the ethnicity difference in the demographic and diabetic characteristics might also influence the different results between the Chinese and non-Chinese populations [28][29][30].…”