Does eGFR improve the diagnostic capability of S-Creatinine concentration results? A retrospective population based study

Kallner, Anders; Ayling, Peter A; Khatami, Zahra

doi:10.7150/ijms.5.9

Cited by 21 publications

(17 citation statements)

References 15 publications

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“…Creatinine Kit that made by (Human company/ Spain) was used to determine the concentration of serum creatinine according to the (Kallner et al, 2008).…”

Section: Creatinine Testmentioning

confidence: 99%

In Vivo and In Vitro Antibacterial Activities of Cranberry Extract against E. coli O157:H7 in Urinary Tract Infected Rats

Ibrahim¹

2015

Adv. Anim. Vet. Sci.

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| The objective of this study was to determine the in-vitro and in-vivo activity of cranberry extracts against Escherichia coli O157:H7. This strain of E. coli was the most common etiologic agent of urinary tract infections isolated from patients. Filter sterilized aqueous and methanol extract of cranberry was prepared and used in the present study. The aqueous extract of cranberry produced inhibition zone ranging from (10.8 -23.8) mm against the tested bacteria. While the methanol extract produces larger zones of inhibition (12.1 -24.2) mm against the bacteria. The minimum inhibitory concentration (MIC) for the methanol and aqueous extract was 0.35 and 0.625 mg/ml, respectively. In vivo study involved inducing UTI in rats and then treated with (200 mg/kg B.W) aqueous and methanol extract and compared with Gentamicin treatment at a dose of (2 mg/kg B.W) subcutaneously for 14 days. Methanol extract succeeded in treated UTI caused by Escherichia coli in the infected rats and prevented infection comparing with aqueous extract and Gentamicin. Food, water intake, body weight, pH and creatinine level returned to normal values after treatment with methanol extract of Cranberry fruit (200mg/Kg. B.W) comparing with aqueous extract of Cranberry fruit and 2mg/Kg. B.W. of Gentamicin. These parameters used in this current study as indicator for curing from infection. These findings indicated that cranberry extract was effective at all levels in inhibiting E. coli O157:H7; thus it possesses antimicrobial activity and hold great promise as an antimicrobial agent. Keywords

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“…Creatinine Kit that made by (Human company/ Spain) was used to determine the concentration of serum creatinine according to the (Kallner et al, 2008).…”

Section: Creatinine Testmentioning

confidence: 99%

In Vivo and In Vitro Antibacterial Activities of Cranberry Extract against E. coli O157:H7 in Urinary Tract Infected Rats

Ibrahim¹

2015

Adv. Anim. Vet. Sci.

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“…For example, recent studies have suggested that the MDRD calculated eGFR was no better than serum creatinine concentration alone in ‘diagnosing’ CKD, using the current KDOQI criteria [25, 26]. The necessity for repeated measurement to confirm the ‘chronicity’ of the decline in eGFR or the persistence of the manifestations of kidney damage imposes a severe limitation upon cross-sectional epidemiological studies.…”

Section: How Accurate Is the Kdoqi Classification In Identifying Ckd?mentioning

confidence: 99%

The Global Burden of Chronic Kidney Disease: How Valid Are the Estimates?

Glassock

Winearls²

2008

Nephron Clin Pract

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Background/Aims: The values for the global prevalence of chronic kidney disease (CKD) are poorly understood. Current classification schemas may overstate the prevalance of CKD. This minireview analyzes the pitfalls in the use of current classification approaches for identifying CKD on a global basis. Methods: Literature review and comment. Results: Published estimates for the global burden of CKD are likely to be incorrect and inflated. Overestimations of prevalence have occurred due to flaws in the classification systems employed and in ascertainment methods. Conclusions: A revision of the current system of diagnosing and classifying CKD is needed in order to determine with greater precision true global burden of CKD. A new system is proposed.

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“…1,6 Knowledge of eGFR could also aid the selection of safe and effective dosing regimens for potentially toxic drugs that are eliminated largely by glomerular filtration, although the superiority of the MDRD-estimated eGFR over other estimates for this purpose is not well established. 7 Undoubtedly, the concept of eGFR has raised the profile of CKD in the community at large.…”

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confidence: 99%

Routine reporting of estimated glomerular filtration rate: not ready for prime time

Glassock

Winearls

2008

Nat Rev Nephrol

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Does eGFR improve the diagnostic capability of S-Creatinine concentration results? A retrospective population based study

Cited by 21 publications

References 15 publications

In Vivo and In Vitro Antibacterial Activities of Cranberry Extract against E. coli O157:H7 in Urinary Tract Infected Rats

In Vivo and In Vitro Antibacterial Activities of Cranberry Extract against E. coli O157:H7 in Urinary Tract Infected Rats

The Global Burden of Chronic Kidney Disease: How Valid Are the Estimates?

Routine reporting of estimated glomerular filtration rate: not ready for prime time

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