Does calculus-related chronic sialadenitis represent a risk state for adenoid cystic carcinoma?

Ide, Fumio

doi:10.1016/j.ijom.2011.06.021

Cited by 4 publications

(5 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is also stated that chronic inflammation due to obstruction by sialoliths could be related to oncogenesis ( 3 , 4 , 5 ). Another view suggests that sialolite and tumor formation could be caused by common predisposing factors rather than a cause-and-effect relationship ( 6 ). Hasegawa et al ( 4 ) reported a case with the coexistence of ACC and sialolithiasis.…”

Section: Discussionmentioning

confidence: 99%

Coexistence of Adenoid Cystic Carcinoma and Sialolithiasis in Submandibular Gland: Case Report

Akın¹,

Sivrice²,

Ayyildiz³

et al. 2023

TAO

View full text Add to dashboard Cite

Sialolithiasis is the primary cause of swelling in the major salivary glands. The etiopathogenesis is not clear. Adenoid cystic carcinoma is a slow-growing salivary gland malignancy with a poor prognosis. There are only a few cases in the literature reporting the coexistence of sialolithiasis and adenoid cystic carcinoma. In this report, we present a case that was thought to have sialolithiasis in the foreground because of the calcified image on computed tomography, but was diagnosed with adenoid cystic carcinoma after excision, together with a discussion of the relationship between sialolithiasis and carcinogenesis.

show abstract

Section: Discussionmentioning

confidence: 99%

Coexistence of Adenoid Cystic Carcinoma and Sialolithiasis in Submandibular Gland: Case Report

Akın¹,

Sivrice²,

Ayyildiz³

et al. 2023

TAO

View full text Add to dashboard Cite

show abstract

“…[3][4][5] According to the examples of Hasegawa et al and our case, long-standing sialolith cases (about 10 years) may be associated with malignancy regardless of age, gender, and sialolith size. 4 Although almost all AdCC cases occur in the absence of previous sialolithiases, 11 according to the evidence, when the patient is aware of a long-standing illness, it may be prudent to rule out the presence of an associated tumor by the extensive radiographic examination, such as CT, sonography, and magnetic resonance imaging (MRI). Among these imaging methods, MRI can delineate various kinds of soft tissue lesions clearly with high resolving contrast.…”

Section: Discussionmentioning

confidence: 99%

“…3,4,13,14 We think that, as mentioned by Ide, predisposing factors for sialolith formation can induce simultaneous initiation of carcinogenesis. 11 However, an accumulation of similar cases is needed to elucidate the association between AdCC carcinogenesis and sialolithiasis.…”

Section: Discussionmentioning

confidence: 99%

Adenoid Cystic Carcinoma With Sialolithiasis of the Left Submandibular Gland: A Case Report and Literature Review

et al. 2018

View full text Add to dashboard Cite

Adenoid cystic carcinoma is one of the most common salivary gland malignancies with poor long-term prognosis, but the coexistence of sialoliths is extraordinarily rare. In this article, we report a case of 30-year-old woman with a history of submandibular area swelling with intermittent pain increasing during mealtimes that had led her attending physician to diagnose a sialolith in the left submandibular gland on a radiograph 10 years before. However, the surgical specimen proved to be an adenoid cystic carcinoma accompanied with a sialolith. Histopathologically, the submandibular gland was displaced with a fibrous granulation tissue containing a small cribriform carcinoma invading the extracapsular region of the gland. We performed fluorescence in situ hybridization examination with an MYB-NFIB fusion probe of the lesion, with positive results. The patient underwent a supraomohyoid neck dissection as additional procedure because of the possibility of the extracapsular cancer nest remaining around the submandibular gland, but she remains well and disease free 11 years after the first operation.

show abstract

“…On the other hand, a malignant salivary gland tumor accompanying sialolithiasis are extremity rear. Ide indicated that epithelial salivary gland tumor preceded by chronic obstructive sialadenitis is presently unavailable from epidemiologic data and careful assessment must be taken to ensure that neoplasm is secondary to inflammation [12]. The mechanisms underlying the onset of AdCC a remain to be clarified.…”

Section: Discussionmentioning

confidence: 99%

A quite-small adenoid cystic carcinoma in a patient with parotid gland sialolithiasis

Takano¹,

Watanabe²,

Matsuzaka³

2017

Oral Health Care

View full text Add to dashboard Cite

We present herein a rare case of a quite-small adenoid cystic carcinoma (AdCC) found coincidentally during an operation to remove a sialolith in the parotid gland. The patient was a 64-year-old man. The computed tomography revealed a sialolith-like radiopaque lesion in the left parotid gland. Chronic parotiditis and parotid gland sialolithiasis were diagnosed and an operation performed under general anesthesia to remove the sialolith. During removal of the 2 × 6-mm sialolith from the superficial layer of the parotid gland, a 3 × 4-mm hard opalescent mass was identified slightly posterior to the sialolith and removed concomitantly. Histopathological examination of the mass revealed an adenoid cystic carcinoma. Therefore, the superficial layer of the left parotid gland was excised as second surgery. The postoperative course is good, with no sign of local recurrence or pulmonary metastasis.

show abstract

Does calculus-related chronic sialadenitis represent a risk state for adenoid cystic carcinoma?

Cited by 4 publications

References 5 publications

Coexistence of Adenoid Cystic Carcinoma and Sialolithiasis in Submandibular Gland: Case Report

Coexistence of Adenoid Cystic Carcinoma and Sialolithiasis in Submandibular Gland: Case Report

Adenoid Cystic Carcinoma With Sialolithiasis of the Left Submandibular Gland: A Case Report and Literature Review

A quite-small adenoid cystic carcinoma in a patient with parotid gland sialolithiasis

Contact Info

Product

Resources

About