Do the human umbilical cord blood CD34+ progenitor cells home in the pancreas and kidney of diabetic mice?

Abd-Elhalim, Dalia M; El‐Wazir, Yasser

doi:10.1007/s13410-015-0424-y

Cited by 1 publication

(1 citation statement)

References 27 publications

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“…Information on DNA extraction method, PCR detection method, primer/probe sequences, and the units for cell quantification was investigated from the literatures on cell quantification using Alu-qPCR ( Supplementary Table 3 [ 46 , [48] , [49] , [50] , [51] , [52] , [53] , [54] , [55] , [56] , [58] , [59] , [60] , [61] , [62] , [63] , [64] , [65] , [66] , [67] , [68] , [69] , [70] , [71] , [72] , [73] , [74] , [75] , [76] , [77] , [78] , [79] , [80] , [81] , [82] , [83] , [84] , [85] , [86] , [87] , [88] ], and the trend was summarized in Fig. 3 .…”

Section: Case Studies On Cell Quantification By Qpcr Techniquesmentioning

confidence: 99%

Biodistribution studies for cell therapy products: Current status and issues

Kamiyama

Naritomi

Moriya

et al. 2021

Regenerative Therapy

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Information on the biodistribution (BD) of cell therapy products (CTPs) is essential for prediction and assessment of their efficacy and toxicity profiles in non-clinical and clinical studies. To conduct BD studies, it is necessary to understand regulatory requirements, implementation status, and analytical methods. This review aimed at surveying international and Japanese trends concerning the BD study for CTPs and the following subjects were investigated, which were considered particularly important: 1) comparison of guidelines to understand the regulatory status of BD studies in a global setting; 2) case studies of the BD study using databases to understand its current status in cell therapy; 3) case studies on quantitative polymerase chain reaction (qPCR) used primarily in non-clinical BD studies for CTPs; and 4) survey of imaging methods used for non-clinical and clinical BD studies. The results in this review will be a useful resource for implementing BD studies.

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