Do Roentgen-Ray Treatments as Given by Skin Specialists Produce Cancers or Other Sequelae?

Sulzberger, Marion B.; Baer, Rudolf L.; Борота, А. В.

doi:10.1001/archderm.1952.01530250003001

Cited by 59 publications

(8 citation statements)

References 4 publications

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“…Certain other studies are also not considered because of small sample sizes, short follow-up times or other factors that make interpretation problematic (Sulzberger et al 1952, Rowell 1973, Veien et al . Certain other studies are also not considered because of small sample sizes, short follow-up times or other factors that make interpretation problematic (Sulzberger et al 1952, Rowell 1973, Veien et al .…”

Section: Radiation-induced Skin Cancer Mortalitymentioning

confidence: 99%

Overview of Radiation-induced Skin Cancer in Humans

Shore

1990

International Journal of Radiation Biology

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There are about a dozen studies of the incidence of skin cancer among irradiated populations with known skin doses that are available for estimating the risk of radiation-induced skin cancer. It is of note that they provide no evidence for a dose threshold and are compatible with a linear dose-response relationship, at least for ultraviolet radiation exposed skin. The studies also provide varying amounts of evidence concerning a number of other important issues in assessing skin cancer risk: types of skin cancer induced by ionizing radiation, the appropriateness of relative risk vs absolute risk models, combined effects of ionizing and UV radiations, and variations in sensitivity to skin cancer induction among demographic and genetic subgroups. Little epidemiological information is available on several factors, such as the RBE for high-LET radiation, the effects of dose protraction or fractionation, or variations in risk by age at irradiation. A reasonable estimate of skin cancer lethality was 0.2 per cent when weighted for the relative proportions of squamous cell and basal cell skin cancers. Average risk estimates of radiation-induced skin cancer incidence were: absolute risk (AR) of 8.5 X 10(-4) person-year-Sv and excess relative risk (RR) of 52 per cent/Sv. Lifetime skin cancer risk was calculated by life-table methods for males from exposures spread out over ages 20-60 years. The estimates for excess skin cancer incidence were 2 per cent and 11 per cent per Sv under the AR and RR models, respectively, while the corresponding mortality risks were 4 X 10(-5) and 2 X 10(-4) per Sv.

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Section: Radiation-induced Skin Cancer Mortalitymentioning

confidence: 99%

Overview of Radiation-induced Skin Cancer in Humans

Shore

1990

International Journal of Radiation Biology

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“…In our review of the literature, radiodermatitis and basal‐cell epithelioma were noted following as little as 400 rads and after as much as 6,000 rads. Alternatively, 4,000 rads have been given in fractionated doses without sequelae whatsoever 38 . Some studies are not reliable because they were reported prior to standardization of radiation.…”

Section: Discussionmentioning

confidence: 99%

Basal‐Cell Carcinoma Occurring in an Axilla: A Case Presentation and a Review of Factors Related to Tumor Development

Susong

Ratz

1985

The Journal of Dermatologic Surgery and Oncology

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“…In this way three courses of 300 R can be given quite safely in a lifetime. It has been found that a total cumulative dose of 1000 R per area is quite safe ,, …”

Section: Practical Aspects Of Superficial Radiotherapymentioning

confidence: 99%

“…Sometimes the skin becomes thickened, and ulceration occurs in sites of trauma. Additional exposure to ultraviolet light and aging worsen chronic radiodermatitis …”

Section: Adverse Effects Of Conventional Superficial X‐ray Therapymentioning

confidence: 99%

Adverse Effects of Superficial X‐Ray Therapy and Recommendations for Safe Use in Benign Dermatoses

Rowell

1978

The Journal of Dermatologic Surgery and Oncology

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Do Roentgen-Ray Treatments as Given by Skin Specialists Produce Cancers or Other Sequelae?

Cited by 59 publications

References 4 publications

Overview of Radiation-induced Skin Cancer in Humans

Overview of Radiation-induced Skin Cancer in Humans

Basal‐Cell Carcinoma Occurring in an Axilla: A Case Presentation and a Review of Factors Related to Tumor Development

Adverse Effects of Superficial X‐Ray Therapy and Recommendations for Safe Use in Benign Dermatoses

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