Do Endoscopic Bariatric Procedures Improve Postprocedural Quality of Life and Mental Health? A Systematic Review and Meta-analysis

Gadd, Nicola; McIntosh, Ashleigh; Fear-Keen, Brianna; Hoult, Jennifer; Maimone, Isabella R.

doi:10.1007/s11695-020-04860-2

Cited by 10 publications

(4 citation statements)

References 48 publications

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“…Some studies have already described the relationship between endoscopic bariatric treatments and improvement in quality of life. A metanalysis by Gadd et al including studies on several bariatric endoscopic techniques showed that they may improve short-term quality of life and mental health alongside weight loss [ 22 ]. With a specific view on ESG, Mehta et al showed a continuous positive association between the maximum weight loss achieved after ESG and the improvement in quality of life assessed with several validated questionnaires [ 23 ].…”

Section: Discussionmentioning

confidence: 99%

Success Predictors of Endoscopic Sleeve Gastroplasty

Matteo,

Bove,

Ciasca

et al. 2024

OBES SURG

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Objective Endoscopic sleeve gastroplasty (ESG) is a minimally invasive procedure that proved to be safe and effective in obesity treatment. However, not all subjects respond to treatment in the same way, and, with a view to personalized care, it is essential to identify predictors of success or failure. Methods A retrospective 2-year followed-up cohort of ESG subjects was analyzed to investigate the presence of any baseline or early indicators of long-term optimal or suboptimal ESG outcomes. Results A total of 315 subjects (73% women) were included, with 73% of patients exhibiting an Excess weight loss percentage (%EWL) >25% at the 24 months. Neither demographic parameters (age and sex), smoking habits, and menopause in women nor the presence of comorbidities proved potential predictive value. Interestingly, the %EWL at 1 month after ESG was the strongest predictor of 24-month therapeutic success. Subsequently, we estimated an “early threshold for success” for 1 month-%EWL by employing Youden’s index method. Conclusions ESG is a safe and effective bariatric treatment that can be offered to a wide range of subjects. Early weight loss seems to impact long-term ESG results significantly and may allow proper early post-operative care optimization. Graphical Abstract

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Section: Discussionmentioning

confidence: 99%

Success Predictors of Endoscopic Sleeve Gastroplasty

Matteo,

Bove,

Ciasca

et al. 2024

OBES SURG

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“…In a recent meta-analysis that included 21 studies, IGBs significantly improved postprocedure quality of life (QoL) and mental health [28]. In a small prospective study of 14 patients, duration of physical activity increased by 80% (P < 0.001), and this increase was correlated with improvements in working memory [29].…”

Section: Recent Data On Quality Of Life Improvement and Long-term Eff...mentioning

confidence: 99%

Endobariatrics: well past infancy and maturing rapidly

Shrestha

Shah

2022

Current Opinion in Gastroenterology

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Purpose of reviewThis review summarizes the key developments with regard to FDA-approved endoscopic bariatric metabolic therapies (EBMTs) in the last 2 years.Recent findingsThe prevalence of obesity has increased during the coronavirus disease 2019 (COVID-19) pandemic, and obesity worsens COVID-19 related outcomes. Several studies have confirmed the safety and short-term efficacy of intragastric balloons (IGBs). In the short-term IGBs may improve steatosis and fibrosis in nonalcoholic fatty liver disease and improve quality of life and mental health. Unfortunately weight loss from these temporarily placed devices is not sustained long-term. Endoscopic sleeve gastroplasty (ESG) may be more effective and durable than IGBs, and result in fewer adverse events compared to bariatric surgery. The recently completed MERIT trial may catapult ESG as a first-line EBMT. Aspiration therapy meets safety and effectiveness thresholds for incorporation into routine practice, but overall acceptance has been lower than other FDA-approved EBMTs.SummaryThe field of endobariatrics is rapidly maturing. Significant knowledge gaps remain with regards to combining EBMTs with pharmacologic therapy to improve durability of weight loss. The rapid expansion in the literature supporting safety and long-term efficacy ESG may prompt revision of existing guidelines.

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“…Gadd et al [ 79 ] tried to analyze the impact of endoscopic bariatric procedures, IGBs included, in the improvement of quality of life (QoL) and mental health, assessed by using a validated tool. Twenty studies published between 2008 and 2019 with a total number of 876 participants (77% female) were included, evaluating five different endoscopic procedures.…”

Section: Effectiveness For Body Weight Lossmentioning

confidence: 99%

Six intragastric balloons: Which to choose?

Stavrou¹,

Shrewsbury²,

Kotzampassi³

2021

WJGE

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Endoscopically placed intragastric balloons (IGBs) have played a significant role in obesity treatment over the last 30 years, successfully bridging the gap between lifestyle modification/pharmacotherapy and bariatric surgery. Since they provide a continuous sensation of satiety that helps the ingestion of smaller portions of food, facilitating maintenance of a low-calorie diet, they have generally been considered an effective and reversible, less invasive, non-surgical procedure for weight loss. However, some studies indicate that balloons have limited sustainable effectiveness for the vast majority attempting such therapy, resulting in a return to the previous weight after balloon removal. In this review we try to summarize the pros and cons of various balloon types, to guide decision making for both the physician and the obese individual looking for effective treatment. We analyzed the six most commonly used IGBs, namely the liquid-filled balloons Orbera, Spatz3, ReShape Duo and Elipse, and the gas-filled Heliosphere and Obalon - also including comments on the adjustable Spatz3, and the swallowable Obalon and Elipse - to optimize the choice for maximum efficacy and safety.

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Do Endoscopic Bariatric Procedures Improve Postprocedural Quality of Life and Mental Health? A Systematic Review and Meta-analysis

Cited by 10 publications

References 48 publications

Success Predictors of Endoscopic Sleeve Gastroplasty

Success Predictors of Endoscopic Sleeve Gastroplasty

Endobariatrics: well past infancy and maturing rapidly

Six intragastric balloons: Which to choose?

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