Do Early Fetal Measurements and Nuchal Translucency Correlate With Term Birth Weight?

Hackmon, Rinat; Librach, Clifford; Burwick, Richard M.; Rodrigues, Nicole; Farine, Dan; Berger, Howard

doi:10.1016/j.jogc.2017.04.034

Cited by 5 publications

(5 citation statements)

References 29 publications

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“…In their study on the population grouped as LGA and non-LGA, Weissman et al claimed that increased first trimester NT measurements were associated with LGA (30). Hackmon et al's study in 2017 showed a correlation between birth weight and early fetal measurements such as biparietal diameter (BPD) and crown-rump length (CRL), NT measurements, and NT percentiles (11). There is a predominant opinion in the literature that a correlation exists between LGA and NT measurements (2,10,13,27,30,31), but our study revealed no correlation between NT measurements and non-LGA AGA and SGA groups.…”

Section: Discussioncontrasting

confidence: 67%

The Relationship Between First-Trimester Aneuploidy Markers and Birth Weight

Soysal

Bıyık

Erten

et al. 2021

Gynecol Obstet Reprod Med

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OBJECTIVE: We aimed to determine the relationship between the first-trimester aneuploidy screeningma and the predicted weight at birth: Small for gestational age and large for gestational age. STUDY DESIGN: 594 low-risk pregnant women with a singleton pregnancy, who underwent first-trimester aneuploidy screening by measuring nuchal translucency, maternal serum free beta-human chorionic gonadotropin, and pregnancy-associated plasma protein-A were included in the study. Those weighing above the 3rd percentile and below the 10th percentile were defined as small for gestational age, and those over the 90th percentile were defined as large for gestational age. RESULTS: A total of 594 pregnant women were enrolled. The mean maternal age of the studied group was 28.8±5.5 years. Low maternal serum pregnancy-associated plasma protein-A levels and decreased nuchal translucency measurements were associated with the small for gestational age newborn (p<0.001 and p=0.001, respectively). There is a significant correlation with large for gestational age for newborns only with an increase in maternal serum pregnancy-associated plasma protein-A levels (p=0.001). beta-human chorionic gonadotropin levels were not associated with the birth weight (p=0.735). CONCLUSION: Maternal serum pregnancy-associated plasma protein-A levels, one of the markers in first-trimester aneuploidy screening, can be used in the prediction of small for gestational age and large for gestational age However, due to its low correlation, it is not a suitable screening test for clinical practice.

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Section: Discussioncontrasting

confidence: 67%

The Relationship Between First-Trimester Aneuploidy Markers and Birth Weight

Soysal

Bıyık

Erten

et al. 2021

Gynecol Obstet Reprod Med

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“…In a study of the non-diabetic population, it was shown that an increased first trimester NT was linked to large-for-gestational-age (LGA) neonates (19) . In a study published in 2017 by Hackmon et al (20) , it was reported that early fetal measurements and NT were correlated with term birthweight (20) . Given that previous studies faced problems in accurately determining gestational age, this study involved IVF patients so as to ensure the accuracy of gestational age.…”

Section: Discussionmentioning

confidence: 99%

Fetal nuchal translucency: is there an association with birthweight and neonatal wellbeing?

Kalem¹,

A²,

Bakırarar³

et al. 2019

tjod

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Objective: To evaluate the relationship between nuchal translucency (NT) values with birthweight and the wellbeing of the newborn. Materials and Methods: This retrospective cohort study that included 508 patients made use of data on healthy full-term, singleton, live birth newborns in a university hospital between 2016 and 2018. The relationship between the NT multiple of the median (MoM) value and maternal body mass index, birthweight, sex, need for neonatal intensive care unit (NICU), and APGAR scores was evaluated. Similarly, the relationship between birthweight and NT MoM, and biochemical data in the first trimester was also evaluated. Results: There was a positive correlation between NT and birthweight (p<0.001). The need for NICU admission increased (p=0.001), and APGAR 1st minute scores decreased (p=0.001) with increasing NT, and APGAR 5th minute scores remained unchanged (p=0.057). Conclusion: The present study identified a positive correlation between first trimester NT and birthweight, and a negative correlation with the wellbeing of the neonate.

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“…Yet, some first-trimester parameters have been associated with adverse pregnancy outcomes. For example, low levels of PAPP-A and beta-hCG in first-trimester maternal serum, high uterine PI and/or notching in the waveform of uterine artery Doppler could be associated with low birth weight (Shwarzman et al, 2013;Zhu et al, 2015;Gundu et al, 2016;Sirikunalai et al, 2016;Stampalija et al, 2017) and first-trimester CRL could correlate positively with birthweight (Hackmon et al, 2017). Currently, PAPP-A and uterine artery PI are even recognized to be predictive of placenta-related diseases such as preeclampsia and small for gestational age .…”

Section: Introductionmentioning

confidence: 99%