2010
DOI: 10.1016/j.bioelechem.2009.09.007
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Do copper ions activate tyrosinase enzyme? A biosensor model for the solution

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Cited by 59 publications
(27 citation statements)
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“…In addition, the GT culture accumulated a higher level of yellowish pigments in CD + CuSO 4 than either the WT or GT on CD medium alone. These results are consistent with the requirement of a copper cofactor for the activity of tyrosinase enzyme (Akyilmaz et al, 2010). The addition of L-Dopa to CD resulted in the melanogenesis of the culture medium due to non-enzymatic oxidation.…”
Section: Characterization Of the Tyr Gene Over-expression Mutantsupporting
confidence: 91%
“…In addition, the GT culture accumulated a higher level of yellowish pigments in CD + CuSO 4 than either the WT or GT on CD medium alone. These results are consistent with the requirement of a copper cofactor for the activity of tyrosinase enzyme (Akyilmaz et al, 2010). The addition of L-Dopa to CD resulted in the melanogenesis of the culture medium due to non-enzymatic oxidation.…”
Section: Characterization Of the Tyr Gene Over-expression Mutantsupporting
confidence: 91%
“…At higher concentrations, standard curve showed a deviation from the linearity. Limit of detection was calculated as 2.5 × 10 −8 M by using 3S b /m formula (Akyılmaz et al, 2010). The LOD value obtained is both lower than many other reports based on carbon paste detecting Pb(II) ions (Friberg, 1977;Ganjali et al, 2010;Mojica et al, 2007;Yao and Ramelow, 1998), and the Pb(II) limit determined by EPA.…”
Section: Some Analytical and Technique Specifications Of The Developementioning
confidence: 99%
“…The commonly used enzymes for this purpose are oxidoreductases, polyphenol oxidases, peroxidases, and aminooxidases. [5][6][7] The first microbe-based or cell-based sensor was actualized by Diviès. 8 The tissues for tissue-based sensors arise from plant and animal sources.…”
Section: Types Of Biosensorsmentioning
confidence: 99%