Do biomaterials cause implant-associated mesenchymal tumors of the breast? Analysis of 8 new cases and review of the literature

Balzer, Bonnie; Weiss, Sharon W.

doi:10.1016/j.humpath.2009.03.020

Cited by 43 publications

(31 citation statements)

References 37 publications

(34 reference statements)

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“…In all nine of those cases, the tumor had a well-defined border, including one case with an aggressive appearance in which the tumor destroyed adjacent bone and invaded the chest wall [6]. Sarcoma has also been reported to develop in association with breast implants, and breast sarcoma also exhibits a relatively smooth border [19]. However, cases of post-implant sarcoma are extremely rare (five cases have been reported in the literature), and it typically occurs after a longer latency (median of 10 years) [19].…”

Section: Discussionmentioning

confidence: 98%

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Breast fibromatosis associated with breast implants

et al. 2015

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Fibromatosis refers to an extra-abdominal desmoid tumor or aggressive fibromatosis. Breast fibromatosis can develop in association with the capsule around a breast implant, although reports of cases of fibromatosis associated with breast implants are rare. As the demand for breast augmentation has increased, it is important to understand the diseases associated with breast implants. In the present report, we describe a case of breast fibromatosis that developed adjacent to a breast implant and demonstrated a relatively well-defined border even though it invaded the surrounding structures. We also explore the specific imaging features for diagnosing breast fibromatosis in association with implants by reviewing previous literature.

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Section: Discussionmentioning

confidence: 98%

“…Sarcoma has also been reported to develop in association with breast implants, and breast sarcoma also exhibits a relatively smooth border [19]. However, cases of post-implant sarcoma are extremely rare (five cases have been reported in the literature), and it typically occurs after a longer latency (median of 10 years) [19].…”

Section: Discussionmentioning

confidence: 99%

Breast fibromatosis associated with breast implants

et al. 2015

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“…fibromatosis, lipomatous tumors or sarcomas) are known to be associated with breast silicone implants. [10] These neoplasms are infrequent and differential diagnosis could be established using histopathological analyses along with IHC staining for S100 protein. Although malignant mesenchymal tumors were not reported among patients with ruptured PIP implants, we performed IHC analyses of S100 expression in our patient, which is in agreement with other studies.…”

Section: Discussionmentioning

confidence: 99%

An unusual case of a ruptured Poly Implant Prothèse breast implant associated with xanthoma

Dinets

Unukovych

Khrapach

et al. 2016

Case Reports in Plastic Surgery and Hand Surgery

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“…Nevertheless, the authors concluded that surgical trauma, perhaps occurring in patients with a predisposition to develop desmoid tumors, could account for fibromatosis in this setting and that the relationship between implants and the sarcoma was probably casual. 189 The rare finding of an anaplastic large cell lymphoma of the breast and silicone breast implants is probably coincidental. 190 Local reactions at the sites of injections include pain, erythema, ecchymosis, hyperpigmentation and hypopigmentation of the overlying skin, induration and inflammatory nodules, also named ''siliconomas,'' which are sometimes resolved with dystrophic scars.…”

Section: Poly-l-lactic Acid Key Pointsmentioning

confidence: 99%