DNA sequencing of HLA-B alleles in Mexican patients with Takayasu arteritis

Vargas‐Alarcón, Gilberto; Zúñiga, Joaquı́n; Gamboa, Ricardo; Hernández-Pacheco, Guadalupe; Hesiquio, R; Cruz, David; Martínez-Baños, Déborah; Portal-Celhay, Cynthia; Granados, Julio; Reyes, Pedro A.

doi:10.1016/s0167-5273(00)00188-1

Cited by 31 publications

(18 citation statements)

References 22 publications

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“…[21][22][23] For example, in Japan and Korea there is a clear association with the extended haplotype: HLA B*52, DRB1*1502, DRB5*0102, DQA1*0103, DQB1*0601, DPA1*02-DPB1*0901. 21 Sequence analysis has shown that some of the alleles share specific epitopes and it may be that the epitopes are more important as a disease susceptibility factor than the allele in which they are found.…”

Section: Histology Immunology and Pathogenesismentioning

confidence: 99%

Takayasu arteritis: a review

Johnston

Lock²,

Gompels³

2002

Journal of Clinical Pathology

644

510

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Section: Histology Immunology and Pathogenesismentioning

confidence: 99%

Takayasu arteritis: a review

Johnston

Lock²,

Gompels³

2002

Journal of Clinical Pathology

644

510

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“…Alarcón et al demostraron HLA B*15, B*39 y B*40 en (14) la mayoría de sus pacientes mexicanos . Sin embargo, Salazar et al describen presencia de HLA-DRB1*1602 and HLA-DRB1*1001 en una población (15) colombiana .…”

Section: Discussionunclassified

Takayasu arteritis in a child: A case report

Morel

Marecos

Ávila

et al. 2017

Pediatr. (Asunción)

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“…[7][8][9] Specific residues in the HLA molecule could also confer genetic susceptibility to TB, because several HLA alleles have been found to be associated with the disease in different populations. Therefore, the similar clinical features that TA and TB present could be better explained by the effect of a specific sequence rather than the effect of a specific allele.…”

Section: Discussionmentioning

confidence: 99%

“…2,7 Sequencing of HLA-B alleles in Mexican patients showed that these alleles share residues with Asian alleles (-B51, -B52, and -B39) associated with the disease. 8,9 On the other hand, a possible relationship between TA and tuberculosis (TB) has been proposed because of the similarities of the chronic inflammatory lesions in both diseases, as well as, in some cases, occlusive lesions on arterial walls in some examples of advanced pulmonary TB. [10][11][12] In addition, the rare coexistence of TA with pulmonary or extrapulmonary TB, the high frequency of skin delayed hypersensitivity to mycobacterial antigens in the form of purified protein derived (PPD) and a single case of improvement of TA when TB has been successfully treated, [13][14][15][16] suggest a possible link between these diseases.…”

Section: Introductionmentioning

confidence: 99%

Comparative study of the residues 63 and 67 on the HLA‐B molecule in patients with Takayasu's arteritis and tuberculosis

Vargas‐Alarcón

Soto

Pérez-Hernández

et al. 2008

Cell Biochemistry & Function

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Takayasu's arteritis (TA) and tuberculosis (TB) have been associated with major histocompatibility complex genes, especially HLA-B alleles. However, different HLA-B alleles have been detected in these diseases. The aim of the study was to compare the distribution of the residues 63 and 67 on the HLA-B molecule in patients with TA and TB in order to establish a genetic relationship between these two diseases. HLA-B sequences obtained in 30 patients with TB were compared to those previously reported in TA and healthy controls. 8 out of 30 TB patients studied (26.6%) presented at least one allele with glutamic acid at position 63 and serine at position 67. This was observed in 73% of the TA patients (p = 0.0005). Ten TB (10/30 = 33.3%) and two TA patients (2/26 = 7.7%) did not show similarity at the mentioned positions (p = 0.019). This preliminary study suggests a difference in the distribution of the residues 63 and 67 of the HLA-B alleles in patients with TA and TB.

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DNA sequencing of HLA-B alleles in Mexican patients with Takayasu arteritis

Cited by 31 publications

References 22 publications

Takayasu arteritis: a review

Takayasu arteritis: a review

Takayasu arteritis in a child: A case report

Comparative study of the residues 63 and 67 on the HLA‐B molecule in patients with Takayasu's arteritis and tuberculosis

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