DNA monolayers complexed with amphiphilic intercalator at the air-water interface

The pH stimulated reversible loading and release of a cationic dye in a layer-by-layer assembled DNA/PAH film

“…Various efforts have been made to immobilize the DNA. For example, Okahata et al have mixed DNA and cationic lipids in an aqueous solution and then synthesized a series of polyion complexes of DNA and lipids [6][7][8][9][10]. DNA could also be immobilized by mixing with polycations in solution, and some properties have been reported [11][12][13].…”

Stretching of Single Dna Molecules by Langmuir–blodgett Method

“…We have reported that a monomolecular film of DNA can be prepared by using a polyion complex technique. 7 When a chloroform solution of a cationic amphiphile was spread on an aqueous dsDNA subphase, a polyion complex film of the cationic amphiphile and dsDNA was formed by electrostatic interaction at the air-water interface. This film was transferred on a clean glass substrate by a vertical lifting method.…”

A novel biological active multilayer film based on polyoxometalate with pendant support-ligand

“…However, DNA is highly water-soluble and biochemically unstable. Stabilizing DNA by immobilization on a solid support is important for the utilization of DNA as functional materials [16][17][18]. Physically adsorbed biomolecules can be readily lost and are often prone to denaturation and thereby to lose their biocatalytic or biorecognition activities.…”